{"id":"W3045548795","doi":"10.1210/clinem/dgaa484","title":"International Histopathology Consensus for Unilateral Primary Aldosteronism","year":2020,"lang":"en","type":"article","venue":"The Journal of Clinical Endocrinology & Metabolism","topic":"Hormonal Regulation and Hypertension","field":"Medicine","cited_by":289,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; University Health Network","funders":"National Institute of General Medical Sciences; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; European Research Council; U.S. Department of Veterans Affairs; Else Kröner-Fresenius-Stiftung; Deutsche Forschungsgemeinschaft; Japan Society for the Promotion of Science","keywords":"Primary aldosteronism; Histopathology; Medicine; Hyperaldosteronism; Aldosterone synthase; Pathology; H&E stain; Aldosterone; Immunohistochemistry; Internal medicine; Blood pressure","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0334898,0.0007509166,0.001147429,0.006526774,0.002593309,0.002507709,0.005587206,0.00340884,0.002900021],"category_scores_gemma":[0.02798386,0.0006183877,0.001857389,0.002576998,0.002193603,0.002180576,0.004191893,0.003849508,0.002928881],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003593483,"about_ca_system_score_gemma":0.01529521,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006751133,"about_ca_topic_score_gemma":0.006566566,"domain_scores_codex":[0.9821884,0.005574772,0.004144792,0.001136078,0.005783223,0.001172701],"domain_scores_gemma":[0.9516224,0.003639651,0.003862863,0.00433865,0.03365264,0.002883881],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004910805,0.0002727671,0.04768928,0.004783581,0.0003138856,0.00509449,0.003555011,0.003469507,0.02247277,0.02692679,0.3166335,0.5682974],"study_design_scores_gemma":[0.0001595686,0.0003232918,0.05398069,0.007101258,0.0003778902,0.01415337,0.003957432,0.004812569,0.007927694,0.02328782,0.8837196,0.0001987635],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.1157085,0.09796499,0.3683103,0.1452142,0.04909057,0.007223524,0.004676805,0.003428406,0.2083827],"genre_scores_gemma":[0.3733764,0.03396007,0.5131552,0.01490508,0.007007246,0.005190176,0.01145785,0.001016114,0.03993183],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.0334898,"threshold_uncertainty_score":0.1771131,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1236624693914792,"score_gpt":0.3928825229794885,"score_spread":0.2692200535880093,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}