{"id":"W3045623360","doi":"10.1113/jp279961","title":"Vitamin D is an endogenous partial agonist of the transient receptor potential vanilloid 1 channel","year":2020,"lang":"en","type":"article","venue":"The Journal of Physiology","topic":"Ion Channels and Receptors","field":"Neuroscience","cited_by":44,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Medical Association; University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Transient receptor potential channel; Endogeny; Agonist; Endogenous agonist; Chemistry; Partial agonist; Pharmacology; Transient (computer programming); Receptor; TRPV1; Biophysics; Medicine; Neuroscience; Endocrinology; Biochemistry; Biology; Computer science","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002295641,0.0001298675,0.0002784179,0.00002589609,0.000225637,0.000008819535,0.000735877,0.00006633771,0.0003106177],"category_scores_gemma":[0.00008205539,0.00006321515,0.0002304669,0.0001770082,0.0003460274,0.00008487579,0.0000754599,0.0003213601,0.00002231939],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001399553,"about_ca_system_score_gemma":0.00007091532,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001130093,"about_ca_topic_score_gemma":6.689007e-7,"domain_scores_codex":[0.9983578,0.0005830457,0.0003963027,0.0001493026,0.0002728221,0.000240781],"domain_scores_gemma":[0.9991361,0.00008623856,0.0004380705,0.0001546816,0.00007549291,0.0001093984],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003387023,0.0001089453,4.048518e-7,0.0000111481,0.00001409527,0.000002169142,0.005888973,0.00147364,0.9907863,0.00003969813,0.001130876,0.0002050937],"study_design_scores_gemma":[0.0004476933,0.00088523,0.00007908636,0.000009486906,0.00003945724,0.00009418002,0.0006013223,0.0006811636,0.9953495,0.0001355383,0.001600862,0.00007653837],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9924071,0.0000360995,0.0001972111,0.005240359,0.001891211,0.0001289933,0.00003177424,0.000007071271,0.00006012219],"genre_scores_gemma":[0.9966223,0.0001743312,0.00001094373,0.002149582,0.0009913761,9.72724e-7,5.009145e-7,0.00001461908,0.00003543002],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005287651,"threshold_uncertainty_score":0.3401046,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05047115410670647,"score_gpt":0.2459447096889157,"score_spread":0.1954735555822092,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}