{"id":"W3045799969","doi":"10.1007/s00109-020-01951-6","title":"Interaction with p53 explains a pro-proliferative function for VHL in cancer","year":2020,"lang":"en","type":"article","venue":"Journal of Molecular Medicine","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Puma; Cancer research; Suppressor; Mdm2; Apoptosis; Biology; In vivo; Tumor suppressor gene; Cancer; Hypoxia (environmental); Chemistry; Carcinogenesis; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001804391,0.0001214207,0.000252221,0.00007086856,0.0000230188,0.000006624864,0.00008125849,0.00006793235,0.00001998313],"category_scores_gemma":[0.0001654658,0.00008542682,0.00007036355,0.0001225948,0.00004199451,0.000008032105,0.0000137355,0.0001625324,3.545246e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002612132,"about_ca_system_score_gemma":0.000159855,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001722895,"about_ca_topic_score_gemma":0.00006010395,"domain_scores_codex":[0.999172,0.00004512454,0.0002965877,0.000163161,0.0001869126,0.0001362263],"domain_scores_gemma":[0.9992847,0.000009305941,0.0002503478,0.00008086003,0.0002568291,0.0001179308],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.002730898,0.00004248359,0.0002604064,0.00004099621,0.0001341357,0.0000106691,0.0005053422,0.0005541568,0.9830243,0.00003066834,0.004137305,0.008528636],"study_design_scores_gemma":[0.01073702,0.008617236,0.002001933,0.0003731007,0.0003369923,0.0001613662,0.001578726,0.0003213744,0.3910342,0.00007768632,0.5844738,0.0002865041],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9189451,0.009296563,0.06175525,0.008083011,0.001194479,0.0004584931,0.000007153097,0.000003740613,0.0002561554],"genre_scores_gemma":[0.9914114,0.0008907063,0.0006881627,0.003292465,0.003588014,0.00004303601,0.00001426308,0.00002184615,0.00005004363],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5919901,"threshold_uncertainty_score":0.3483605,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0240000596768953,"score_gpt":0.3021169891649522,"score_spread":0.2781169294880569,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}