{"id":"W3045805945","doi":"10.1038/s41437-020-0347-3","title":"Adult survival in migratory caribou is negatively associated with MHC functional diversity","year":2020,"lang":"en","type":"article","venue":"Heredity","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":11,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval","funders":"Fonds de recherche du Québec – Nature et technologies; Natural Sciences and Engineering Research Council of Canada; Tata Steel; Hydro-Québec; Agence Nationale de la Recherche; ArcticNet; Government of Canada; Ministère des Forêts, de la Faune et des Parcs","keywords":"Biology; Major histocompatibility complex; Balancing selection; Genetic diversity; Genetics; Allele; Evolutionary biology; MHC class I; Natural selection; Selection (genetic algorithm); Gene; Population; Demography","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001258284,0.0001478072,0.000203413,0.0003558187,0.0002310048,0.0003475783,0.0001414716,0.0002530919,0.001798884],"category_scores_gemma":[0.0005294716,0.0001110618,0.00009291351,0.0001564355,0.0002722132,0.0001450815,0.0002536805,0.0002653874,0.0002240251],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001580067,"about_ca_system_score_gemma":0.0001788214,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002936279,"about_ca_topic_score_gemma":0.009442322,"domain_scores_codex":[0.9999049,0.00002130236,0.000003349847,0.00002489444,0.000009502251,0.00003606729],"domain_scores_gemma":[0.9994824,0.00008358643,0.0001690239,0.00003495664,0.0000399268,0.0001900566],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001305646,0.000104536,0.7105485,0.00003784679,0.0001215031,0.0003947873,0.0003903222,0.0001976512,0.2799819,0.0001203393,0.0002006226,0.006596312],"study_design_scores_gemma":[0.000002844685,0.0001462372,0.997955,0.000003789252,0.00001861546,0.0002288672,0.0002389068,0.0001927815,0.001050235,0.00004969228,0.0001098224,0.000003311228],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9997264,0.0001053496,0.00004796679,0.000008746914,0.000001696708,2.400998e-7,0.00002218255,0.000002963461,0.00008455043],"genre_scores_gemma":[0.9993624,0.00005875082,0.00004560254,0.0000113178,0.000003009214,0.000001750187,0.00005614153,0.000002987619,0.0004580168],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002936279,"threshold_uncertainty_score":0.006017923,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02716281048559738,"score_gpt":0.1986688787046015,"score_spread":0.1715060682190041,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}