{"id":"W3045884329","doi":"10.1113/jp280325","title":"The protective role of desmin in duchenne muscular dystrophy: Therapeutic insights","year":2020,"lang":"en","type":"letter","venue":"The Journal of Physiology","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Acadia University; McGill University Health Centre","funders":"","keywords":"Duchenne muscular dystrophy; Dystrophin; Skeletal muscle; ITGA7; Muscular dystrophy; Utrophin; Biology; Sarcolemma; Myokine; Dysferlin; mdx mouse; Dystroglycan; Myopathy; Desmin; Cell biology; Anatomy; Genetics; Extracellular matrix; Immunology; Laminin","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003449586,0.0003402014,0.000458369,0.0006341578,0.0001538161,0.0005366466,0.0003157468,0.0005436484,0.001626588],"category_scores_gemma":[0.0002061581,0.0001001334,0.0003619772,0.0002411898,0.0002607052,0.0004672149,0.0003541204,0.001299452,0.0003022322],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003175209,"about_ca_system_score_gemma":0.0002812189,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003783332,"about_ca_topic_score_gemma":0.0008847109,"domain_scores_codex":[0.9999088,0.00002174822,0.000008276685,0.00001585358,0.00002539978,0.00001994393],"domain_scores_gemma":[0.9999378,0.00001374854,0.0000119329,0.000004051362,0.0000152159,0.00001726221],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001933318,0.001346276,0.00190792,0.005618927,0.0002537696,0.002503669,0.000271191,0.0009013444,0.09702862,0.008651314,0.01832413,0.8612596],"study_design_scores_gemma":[0.002208267,0.00795721,0.0191622,0.003475856,0.000808303,0.0116702,0.0004803566,0.00329705,0.05824041,0.01083195,0.8817545,0.0001136276],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"commentary","genre_scores_codex":[0.04720164,0.9369692,0.00361345,0.004071679,0.0007914106,0.00008524124,0.0001840819,0.000109974,0.006973383],"genre_scores_gemma":[0.3173622,0.66472,0.006417568,0.002301904,0.001230247,0.0001833199,0.0005474776,0.00003480896,0.007202496],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.001626588,"threshold_uncertainty_score":0.005441427,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007287833370967635,"score_gpt":0.217620376835671,"score_spread":0.2103325434647033,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}