{"id":"W3045929109","doi":"10.1016/j.celrep.2020.107972","title":"Bab2 Functions as an Ecdysone-Responsive Transcriptional Repressor during Drosophila Development","year":2020,"lang":"en","type":"article","venue":"Cell Reports","topic":"Neurobiology and Insect Physiology Research","field":"Neuroscience","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Institutes of Health; Baise University; Eunice Kennedy Shriver National Institute of Child Health and Human Development; Austrian Science Fund; National Key Research and Development Program of China; Canadian Institutes of Health Research; Stiftelsen Olle Engkvist Byggmästare; Knut och Alice Wallenbergs Stiftelse; National Natural Science Foundation of China","keywords":"Ecdysone; Ecdysone receptor; Biology; Repressor; Regulation of gene expression; Transcription factor; Cell biology; Gene; Gene expression; Transcriptional regulation; Drosophila melanogaster; Genetics; Nuclear receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001478222,0.0001709307,0.0001883723,0.00007525712,0.0005330215,0.00003035588,0.0001863743,0.0001161178,0.000741551],"category_scores_gemma":[0.0004976587,0.0001631005,0.00007849883,0.0002240043,0.0002142669,0.0002367656,0.0000935242,0.0004104271,0.0003708362],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000279236,"about_ca_system_score_gemma":0.0002697994,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002965578,"about_ca_topic_score_gemma":9.44889e-7,"domain_scores_codex":[0.9978436,0.0002547683,0.0003755551,0.0009170271,0.0002347006,0.0003743376],"domain_scores_gemma":[0.9990591,0.0001152937,0.0001231332,0.0003637363,0.00006124088,0.0002775214],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002876398,0.0001242277,0.0004804456,0.00001926165,0.000005070163,0.001708683,0.000437547,0.00008547187,0.996335,0.0001204433,0.0003512855,0.00004497385],"study_design_scores_gemma":[0.0001920609,0.0002000369,0.02083084,0.000005160991,0.000006349837,0.0006816447,0.000040799,0.00001941963,0.9678858,0.0002991584,0.009664195,0.0001745619],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.989891,0.00002699952,0.00001900382,0.0007652605,0.0003116568,0.0002648632,0.00000595851,0.000146818,0.008568443],"genre_scores_gemma":[0.9940502,0.00001277001,0.00005157245,0.001617827,0.0001496695,0.00006103954,0.00001995208,0.00002235202,0.004014641],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02844917,"threshold_uncertainty_score":0.8119464,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04688652019893278,"score_gpt":0.2796890407105191,"score_spread":0.2328025205115864,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}