{"id":"W3046085847","doi":"10.3390/molecules25153437","title":"Anti-VCAM-1 and Anti-IL4Rα Aptamer-Conjugated Super Paramagnetic Iron Oxide Nanoparticles for Enhanced Breast Cancer Diagnosis and Therapy","year":2020,"lang":"en","type":"article","venue":"Molecules","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"Memorial University of Newfoundland","funders":"","keywords":"Aptamer; Cancer cell; Cancer research; Chemistry; Cancer; Viability assay; Molecular biology; Circulating tumor cell; Cell; Metastasis; Biology; Medicine; Biochemistry; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002170074,0.0002802735,0.0002448376,0.0002854719,0.00008114309,0.0001442918,0.0002998601,0.0004349905,0.0007791726],"category_scores_gemma":[0.0001639484,0.0002105008,0.0001827421,0.0001313107,0.0001432521,0.0001896438,0.0002061159,0.0003243264,0.0002439056],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003325269,"about_ca_system_score_gemma":0.0001655864,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003468159,"about_ca_topic_score_gemma":0.0004902633,"domain_scores_codex":[0.9998673,0.00002660545,0.000008024735,0.00002957429,0.00004196977,0.0000265952],"domain_scores_gemma":[0.9999436,0.0000126616,0.00001493083,0.000005145837,0.00001460263,0.000008971118],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005741187,0.00002059025,0.00004924035,0.00005954902,0.000003787995,0.00004874829,0.000009381361,0.0002754737,0.9950916,0.000134789,0.0001338571,0.004115567],"study_design_scores_gemma":[0.00002576495,0.0001674275,0.0004959078,0.000007286908,0.00001420802,0.0002287339,0.000006123144,0.008667439,0.9867716,0.00007324494,0.00353468,0.000007501561],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8818728,0.007572843,0.1020841,0.0007120822,0.0002421483,0.0002587359,0.0002360941,0.0007473789,0.006273933],"genre_scores_gemma":[0.9523578,0.002205312,0.03870911,0.0002618463,0.00004667582,0.0002293651,0.0002287107,0.0000465391,0.005914688],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007791726,"threshold_uncertainty_score":0.00260663,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01159358285496408,"score_gpt":0.2607944649196626,"score_spread":0.2492008820646985,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}