{"id":"W3046085847","doi":"10.3390/molecules25153437","title":"Anti-VCAM-1 and Anti-IL4Rα Aptamer-Conjugated Super Paramagnetic Iron Oxide Nanoparticles for Enhanced Breast Cancer Diagnosis and Therapy","year":2020,"lang":"en","type":"article","venue":"Molecules","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"Memorial University of Newfoundland","funders":"","keywords":"Aptamer; Cancer cell; Cancer research; Chemistry; Cancer; Viability assay; Molecular biology; Circulating tumor cell; Cell; Metastasis; Biology; Medicine; Biochemistry; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007031806,0.0002346385,0.0002711396,0.00002952897,0.0001137433,0.00005389457,0.00009437143,0.0001283303,0.000004308183],"category_scores_gemma":[0.00004830266,0.0001973074,0.000075395,0.0001037635,0.0002134896,0.000008194232,0.00007023496,0.00005979589,6.007178e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000004847497,"about_ca_system_score_gemma":0.00002067235,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004143473,"about_ca_topic_score_gemma":0.00001813479,"domain_scores_codex":[0.9988557,0.0000571613,0.0001991842,0.0005273799,0.00008691145,0.0002736436],"domain_scores_gemma":[0.9995087,0.00002391021,0.00007170408,0.000178457,0.00008483722,0.0001323346],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001386773,0.00004401125,0.00422621,0.00002632493,0.00005769317,0.000002363848,0.00004745092,0.000008968058,0.9757679,0.000008721916,0.0003055074,0.01936618],"study_design_scores_gemma":[0.000652705,0.0002644808,0.01141417,0.00002326961,0.00005556039,0.000008047187,0.00007111427,0.0001924092,0.9847612,0.0000253349,0.002244285,0.0002874551],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9922717,0.00437104,0.0007037358,0.002136933,0.00001546924,0.0003010319,0.0001350039,0.00005431075,0.00001075573],"genre_scores_gemma":[0.9840972,0.01137333,0.002677725,0.00155317,0.00007625002,0.0001154687,0.00005390545,0.00003308336,0.00001979396],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01907873,"threshold_uncertainty_score":0.8045962,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01159358285496408,"score_gpt":0.2607944649196626,"score_spread":0.2492008820646985,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}