{"id":"W3046146154","doi":"10.1021/acs.orglett.0c02172","title":"A Mild Method for the Generation and Interception of 1,2-Cycloheptadienes with 1,3-Dipoles","year":2020,"lang":"en","type":"article","venue":"Organic Letters","topic":"Cyclization and Aryne Chemistry","field":"Chemistry","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; American Chemical Society Petroleum Research Fund","keywords":"Chemistry; Trapping; Reactivity (psychology); Dipole; Cycloaddition; Block (permutation group theory); Interception; Computational chemistry; Range (aeronautics); Combinatorial chemistry; Stereochemistry; Organic chemistry; Catalysis; Combinatorics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000352522,0.00007407294,0.00008287909,0.000006345073,0.00005083418,0.00001866161,0.00007339131,0.00002958538,0.0002797743],"category_scores_gemma":[0.00003253165,0.00005075259,0.000025229,0.00005256926,0.00004081784,0.00003921724,0.00002080155,0.00004828244,9.735865e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001055235,"about_ca_system_score_gemma":0.00000902551,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004800831,"about_ca_topic_score_gemma":0.000008107349,"domain_scores_codex":[0.9996151,0.000005992904,0.0001061027,0.0001407995,0.0000622973,0.00006973616],"domain_scores_gemma":[0.9997321,0.00005654777,0.0000635992,0.0000950864,0.00002009655,0.00003258596],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000222908,0.000005466803,0.0004408885,0.00008795838,0.00002692969,2.270829e-7,0.0007906798,0.00001665945,0.9945624,0.0000180387,0.002007307,0.002021185],"study_design_scores_gemma":[0.000415289,0.00001067797,0.0001078717,0.00001499903,0.00004240671,0.000004292971,0.0003968606,0.004941357,0.9921655,0.000002908442,0.001824641,0.00007318776],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8888781,0.0000815177,0.0974675,0.01339038,0.00001712693,0.00005961033,0.00001018087,0.0000307238,0.00006485569],"genre_scores_gemma":[0.9928843,0.000026277,0.003553899,0.003206014,0.000232733,0.00001090217,0.0000278983,0.00001697562,0.00004094732],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1040063,"threshold_uncertainty_score":0.3063333,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02163533448303643,"score_gpt":0.2417692211159573,"score_spread":0.2201338866329209,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}