{"id":"W3046339125","doi":"10.3389/fcell.2020.00701","title":"Interactions With Histone H3 & Tools to Study Them","year":2020,"lang":"en","type":"review","venue":"Frontiers in Cell and Developmental Biology","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"Garron Family Cancer Centre; Canadian Institutes of Health Research; Cancer Research Society","keywords":"Histone code; Chromatin; Histone; Cell biology; Biology; Histone H1; Histone-modifying enzymes; Histone H3; Chromatin remodeling; Histone methyltransferase; Histone H2A; Computational biology; Nucleosome; Genetics; DNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009982217,0.001400223,0.001119227,0.002626375,0.0003831703,0.00137442,0.001521955,0.001460293,0.005704728],"category_scores_gemma":[0.0009268461,0.0005263622,0.0005850365,0.002387546,0.001097851,0.002406265,0.00142231,0.00339182,0.009380504],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001446627,"about_ca_system_score_gemma":0.0009563508,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001136821,"about_ca_topic_score_gemma":0.00140245,"domain_scores_codex":[0.9996924,0.00004557307,0.00002708285,0.00006978271,0.0001302516,0.00003487856],"domain_scores_gemma":[0.9997317,0.0001095528,0.00002814126,0.00002029364,0.00007304761,0.00003726302],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008196229,0.00006322307,0.0001388174,0.01254317,0.00006417993,0.0002155791,0.00008106645,0.0004580021,0.009586591,0.0260249,0.06220908,0.8885334],"study_design_scores_gemma":[0.000004074317,0.00001829859,0.000152071,0.0006478704,0.00001512921,0.0002512186,0.00001326437,0.00004239084,0.001275518,0.002062153,0.9955082,0.000009873912],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001011053,0.994381,0.0007928595,0.0003780936,0.000650052,0.00001100754,0.00004720703,0.00003231904,0.003606366],"genre_scores_gemma":[0.000768344,0.9944833,0.0009065478,0.0003553037,0.0003080675,0.0000220216,0.00009633742,0.00001241936,0.003047605],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.005704728,"threshold_uncertainty_score":0.01908422,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02541825911150389,"score_gpt":0.2828022221637228,"score_spread":0.2573839630522189,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}