{"id":"W3046489096","doi":"10.1016/j.biomaterials.2020.120233","title":"Hydrogel-mediated co-transplantation of retinal pigmented epithelium and photoreceptors restores vision in an animal model of advanced retinal degeneration","year":2020,"lang":"en","type":"article","venue":"Biomaterials","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":47,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta; Lunenfeld-Tanenbaum Research Institute; University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Canada First Research Excellence Fund; Ontario Institute for Regenerative Medicine; Krembil Foundation","keywords":"Transplantation; Retinal degeneration; Retina; Retinal pigment epithelium; Retinal; Retinal regeneration; Retinitis pigmentosa; Anatomy; Ophthalmology; Biology; Neuroscience; Medicine; Surgery","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002218615,0.0003762901,0.000315362,0.0003974792,0.0001792486,0.0003639247,0.0003017739,0.0005955189,0.001021473],"category_scores_gemma":[0.0001289537,0.0001852657,0.0003635516,0.0001525632,0.0002530516,0.0003785031,0.0002338478,0.0006329854,0.0002271428],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002472704,"about_ca_system_score_gemma":0.0002671823,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005712808,"about_ca_topic_score_gemma":0.001049064,"domain_scores_codex":[0.9998324,0.00001547679,0.00001263026,0.00003009872,0.00005988421,0.00004953532],"domain_scores_gemma":[0.9998085,0.00002977483,0.00006872565,0.00001998116,0.00001553382,0.00005747826],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008466359,0.00003406615,0.00003733416,0.0000228703,0.000005122973,0.00007962256,0.000008097851,0.00005475298,0.9989901,0.00006596179,0.00001608892,0.0006012386],"study_design_scores_gemma":[0.00001306103,0.0002142475,0.0009257637,0.000006187968,0.00001999363,0.0002048609,0.00001686874,0.0006386561,0.9973418,0.00002258647,0.0005922255,0.000003669282],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939297,0.001265848,0.003183139,0.00007253078,0.0001187542,0.00003111212,0.0001163832,0.00009211256,0.001190401],"genre_scores_gemma":[0.9925526,0.000618658,0.002813614,0.00003329692,0.00001498443,0.00002356736,0.00009990671,0.00002991539,0.003813417],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001021473,"threshold_uncertainty_score":0.003417194,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01414892331061657,"score_gpt":0.2685603531812263,"score_spread":0.2544114298706097,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}