{"id":"W3046566558","doi":"10.1182/blood.2020007522","title":"Carfilzomib, lenalidomide, and dexamethasone plus transplant in newly diagnosed multiple myeloma","year":2020,"lang":"en","type":"article","venue":"Blood","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":74,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Lenalidomide; Medicine; Carfilzomib; Internal medicine; Multiple myeloma; Minimal residual disease; Neutropenia; Autologous stem-cell transplantation; Transplantation; Regimen; Surgery; Oncology; Clinical endpoint; Chemotherapy; Clinical trial; Leukemia","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001391958,0.0006475353,0.001214842,0.0003363728,0.0002393477,0.0005326975,0.0005494964,0.0004175868,0.0007747898],"category_scores_gemma":[0.0005825087,0.0003199186,0.0007476991,0.000318352,0.0004326247,0.0004998876,0.0002997483,0.001308587,0.0001878377],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008593955,"about_ca_system_score_gemma":0.001140382,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001148418,"about_ca_topic_score_gemma":0.005219777,"domain_scores_codex":[0.9995452,0.0002434619,0.0000257487,0.00006412529,0.00005180569,0.00006966053],"domain_scores_gemma":[0.9995925,0.00005733588,0.0001158386,0.00002619112,0.0000203957,0.0001878081],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.4370454,0.08325751,0.06524844,0.000854291,0.002318542,0.0004538192,0.0004087083,0.003621544,0.0390528,0.0003028767,0.001910484,0.3655256],"study_design_scores_gemma":[0.1947965,0.7164452,0.07698352,0.00005123044,0.0008952349,0.000532382,0.000118185,0.001497154,0.004333861,0.0001324682,0.00417872,0.00003561044],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955816,0.003236426,0.0001454778,0.0001634401,0.00005150217,0.0003845768,0.0001036491,0.0000209729,0.0003124145],"genre_scores_gemma":[0.9962465,0.001728183,0.0006589319,0.0002772788,0.00008471021,0.0003438486,0.0002382907,0.000006060519,0.000416102],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001391958,"threshold_uncertainty_score":0.007361472,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03450849152160632,"score_gpt":0.2749467073629789,"score_spread":0.2404382158413726,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}