{"id":"W3046566558","doi":"10.1182/blood.2020007522","title":"Carfilzomib, lenalidomide, and dexamethasone plus transplant in newly diagnosed multiple myeloma","year":2020,"lang":"en","type":"article","venue":"Blood","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":74,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Lenalidomide; Medicine; Carfilzomib; Internal medicine; Multiple myeloma; Minimal residual disease; Neutropenia; Autologous stem-cell transplantation; Transplantation; Regimen; Surgery; Oncology; Clinical endpoint; Chemotherapy; Clinical trial; Leukemia","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001089293,0.0001944333,0.0004301304,0.00009626118,0.00004671885,0.00002280969,0.0000799556,0.00009178273,0.00007834346],"category_scores_gemma":[0.0003908613,0.0001605991,0.00007332679,0.000238767,0.00006663068,0.00007132707,0.00003879999,0.0002393171,0.00004667184],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003531991,"about_ca_system_score_gemma":0.0001195797,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006515943,"about_ca_topic_score_gemma":0.0003945786,"domain_scores_codex":[0.9985825,0.00007639659,0.0002514549,0.0003910133,0.0002895655,0.0004090117],"domain_scores_gemma":[0.998924,0.0003017981,0.00003482529,0.000181811,0.00003361716,0.0005240121],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.003066656,0.0007969007,0.9544405,0.0002722245,0.0003081294,0.006727638,0.002304721,0.000009041913,0.02038476,0.00001973936,0.0001390669,0.01153056],"study_design_scores_gemma":[0.1039736,0.0009296242,0.8498314,0.0002040615,0.0002492652,0.0001919633,0.0002702895,0.00287005,0.04044876,0.0000168569,0.0007390189,0.000275054],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954985,0.001486158,0.00006116048,0.001561764,0.00002072832,0.0007290966,0.00006634284,0.0000639614,0.0005122822],"genre_scores_gemma":[0.9966598,0.0004772433,0.002053488,0.0004567681,0.000112731,0.00008031275,0.00006394285,0.00002908119,0.00006667528],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1046091,"threshold_uncertainty_score":0.6549041,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03450849152160632,"score_gpt":0.2749467073629789,"score_spread":0.2404382158413726,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}