{"id":"W3046596788","doi":"10.3389/fgene.2020.00855","title":"Radioresistance, DNA Damage and DNA Repair in Cells With Moderate Overexpression of RPA1","year":2020,"lang":"en","type":"article","venue":"Frontiers in Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"Ural Branch, Russian Academy of Sciences; Institut de Radioprotection et de SÛreté Nucléaire","keywords":"Radioresistance; DNA damage; DNA repair; DNA; Cell biology; Biology; Molecular biology; Genetics; Cell culture","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006143873,0.0001359989,0.0001915947,0.00004797047,0.00001377165,0.000005978437,0.0001025044,0.0001030491,0.000001975695],"category_scores_gemma":[0.00001254483,0.000132886,0.00002994134,0.0001175088,0.00006163336,0.000002529291,0.0000672681,0.00008168948,1.53381e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008432459,"about_ca_system_score_gemma":0.00003027945,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003585779,"about_ca_topic_score_gemma":0.00001547644,"domain_scores_codex":[0.9992003,0.00002844025,0.000203113,0.0002940066,0.00009428143,0.0001798476],"domain_scores_gemma":[0.9996482,0.000004084699,0.00004440457,0.0002067345,0.00002007197,0.00007647932],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003160878,0.00003081285,0.02141124,0.0001268404,0.00002318515,0.000009656426,0.0003278589,0.02517521,0.9464449,0.000004012233,0.005651118,0.0004791323],"study_design_scores_gemma":[0.001174035,0.0002712719,0.01252598,0.00007505061,0.00001217218,0.000001456383,0.0002160914,0.02520632,0.9550713,0.00003037418,0.005182633,0.000233276],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.974299,0.003312783,0.02190419,0.00005309384,0.00007061666,0.0001637239,0.00002405793,0.000008349418,0.0001641645],"genre_scores_gemma":[0.9607607,0.0008914024,0.03808634,0.0001098411,0.00004738917,0.000006619667,0.00001439367,0.00002344289,0.00005991855],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01618215,"threshold_uncertainty_score":0.5418932,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004420824142957506,"score_gpt":0.2210064736115272,"score_spread":0.2165856494685697,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}