{"id":"W3046596788","doi":"10.3389/fgene.2020.00855","title":"Radioresistance, DNA Damage and DNA Repair in Cells With Moderate Overexpression of RPA1","year":2020,"lang":"en","type":"article","venue":"Frontiers in Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"Ural Branch, Russian Academy of Sciences; Institut de Radioprotection et de SÛreté Nucléaire","keywords":"Radioresistance; DNA damage; DNA repair; DNA; Cell biology; Biology; Molecular biology; Genetics; Cell culture","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002375039,0.0003379704,0.0004724014,0.000159074,0.0001164863,0.0003707434,0.0002183074,0.0003555318,0.000770621],"category_scores_gemma":[0.0001875598,0.0001034898,0.000315568,0.0001246334,0.0002167225,0.0002254572,0.0001853715,0.000572816,0.0004065487],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001465019,"about_ca_system_score_gemma":0.0001103554,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001687139,"about_ca_topic_score_gemma":0.0001169715,"domain_scores_codex":[0.9997614,0.0000430999,0.00003238422,0.00005785655,0.00006989342,0.00003539578],"domain_scores_gemma":[0.9998285,0.00003973744,0.00005566512,0.00002824064,0.0000212783,0.00002656276],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004744584,0.00001528835,0.0001035664,0.00002333944,0.000003461689,0.00002860879,0.000007643303,0.00003190203,0.9990672,0.00002888481,0.00001351047,0.0006292548],"study_design_scores_gemma":[0.00000669371,0.0002648961,0.004535444,0.000005251339,0.00001503095,0.0002779101,0.00002700984,0.0006886074,0.9927052,0.00004775139,0.001419695,0.000006465864],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9888048,0.002935134,0.006420069,0.0001619339,0.00005492541,0.0000303237,0.0004286954,0.0001818038,0.0009823587],"genre_scores_gemma":[0.9940929,0.001175892,0.002516041,0.00003471331,0.00001189788,0.00004714711,0.000615752,0.0000352595,0.001470477],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000770621,"threshold_uncertainty_score":0.00257802,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004420824142957506,"score_gpt":0.2210064736115272,"score_spread":0.2165856494685697,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}