{"id":"W3046634084","doi":"10.1186/s12879-020-05185-2","title":"Predictive value of TNF-α, IFN-γ, and IL-10 for tuberculosis among recently exposed contacts in the United States and Canada","year":2020,"lang":"en","type":"article","venue":"BMC Infectious Diseases","topic":"Tuberculosis Research and Epidemiology","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention; Rush University; Centers for Disease Control and Prevention; Respiratory Health Association of Metropolitan Chicago; Respiratory Health Association; Emory University; Vanderbilt University","keywords":"Tuberculosis; Medicine; Mycobacterium tuberculosis; Internal medicine; Medical microbiology; Immunology; Interferon gamma; Cytokine; Tumor necrosis factor alpha; Gastroenterology; Prospective cohort study; Pathology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001994138,0.0001437226,0.0003650254,0.00009679947,0.00007693188,0.00001423888,0.00005830619,0.00005847569,0.00002214233],"category_scores_gemma":[0.003398639,0.0001009155,0.00005307612,0.0002292984,0.0001690362,0.00006330709,0.00003929604,0.0001295615,3.765861e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007376959,"about_ca_system_score_gemma":0.0003196457,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_topic_score_codex":0.2855437,"about_ca_topic_score_gemma":0.2665456,"domain_scores_codex":[0.9987007,0.0003003306,0.0002687501,0.0002556278,0.0001832869,0.0002913169],"domain_scores_gemma":[0.9976603,0.001661402,0.0000750685,0.0001320745,0.000140748,0.0003304248],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0009695363,0.000119295,0.9872949,0.000409593,0.0001300761,0.00001308928,0.0004892207,0.0002056462,0.0000891399,0.00008844976,0.009925998,0.0002650686],"study_design_scores_gemma":[0.002716367,0.001240513,0.983019,0.0000722047,0.0001865882,0.000009516651,0.001256908,0.009456655,0.0001852913,0.0001543224,0.001599291,0.000103346],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957514,0.0005086705,0.00006596804,0.002064046,0.00002773164,0.0009776698,0.0004368383,0.0000260932,0.0001415564],"genre_scores_gemma":[0.9962754,0.0007247005,0.00001884236,0.002506373,0.00006727724,0.0001368037,0.0002463664,0.00001462877,0.000009554368],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01899802,"threshold_uncertainty_score":0.746838,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02168963686002672,"score_gpt":0.2773047037193559,"score_spread":0.2556150668593292,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}