{"id":"W3046680154","doi":"10.1155/2020/5305306","title":"Interleukin-10 Induces Expression of Neuroendocrine Markers and PDL1 in Prostate Cancer Cells","year":2020,"lang":"en","type":"article","venue":"Prostate Cancer","topic":"Cancer, Stress, Anesthesia, and Immune Response","field":"Medicine","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"Vancouver Coastal Health Research Institute; University of British Columbia; Vancouver Coastal Health","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Enzalutamide; Prostate cancer; Medicine; Neuroendocrine differentiation; Androgen receptor; Immune system; Cancer research; Prostate; Interleukin 10; Internal medicine; Cancer; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007246652,0.0001833152,0.0001387585,0.000181914,0.0001047233,0.0002316023,0.00007721632,0.0001417825,0.002403047],"category_scores_gemma":[0.00007385265,0.0001202905,0.0002516089,0.0001548059,0.0001303969,0.00009977149,0.0001580498,0.0006846125,0.0004428304],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002918633,"about_ca_system_score_gemma":0.0002142584,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007760489,"about_ca_topic_score_gemma":0.001326358,"domain_scores_codex":[0.9998922,0.00001715243,0.00000707353,0.00001638811,0.00002659231,0.00004061469],"domain_scores_gemma":[0.999923,0.00001810497,0.00001281343,0.000009439542,0.00001242595,0.00002431936],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002043837,0.0001376844,0.0005557346,0.00006013759,0.000006192505,0.00007557726,0.00005106625,0.00007751207,0.9958112,0.0001416718,0.0002255673,0.00265328],"study_design_scores_gemma":[0.0000647727,0.001343116,0.01525644,0.00001267997,0.00001615588,0.0003157222,0.000157851,0.001399103,0.9728832,0.00009214779,0.008450842,0.000008084862],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9903985,0.002064689,0.001799275,0.0002195881,0.0001058905,0.00004956109,0.0004695038,0.00007636349,0.004816681],"genre_scores_gemma":[0.9943479,0.0005959541,0.0008967938,0.0001065963,0.00001383509,0.00003277257,0.000499218,0.000006745983,0.003500229],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002403047,"threshold_uncertainty_score":0.008038998,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01610765164092323,"score_gpt":0.2737997025828299,"score_spread":0.2576920509419067,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}