{"id":"W3046708916","doi":"10.1021/acs.langmuir.0c01497","title":"Role of Charge in Lipid Vesicle Binding and Vesicle Surface Saturation by Gaduscidin-1 and Gaduscidin-2","year":2020,"lang":"en","type":"article","venue":"Langmuir","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Memorial University of Newfoundland","funders":"Natural Sciences and Engineering Research Council of Canada; Government of Canada","keywords":"Vesicle; Peptide; Chemistry; Binding constant; Surface charge; Binding site; Biophysics; Biochemistry; Membrane; Biology; Physical chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002783235,0.0003086216,0.0003302148,0.0001919678,0.0001684426,0.000649623,0.0003423158,0.0003672302,0.0006244138],"category_scores_gemma":[0.0007147776,0.00025582,0.0002244714,0.0001380671,0.000305176,0.0004590544,0.0004262183,0.0003684128,0.0001728553],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005686499,"about_ca_system_score_gemma":0.00028948,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001435184,"about_ca_topic_score_gemma":0.0009252592,"domain_scores_codex":[0.999734,0.00005233534,0.00001914448,0.00004330715,0.00007839461,0.00007280705],"domain_scores_gemma":[0.9996212,0.0001670148,0.00006912645,0.0000153905,0.0000725052,0.00005481149],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009495961,0.00001195385,0.0007313953,0.00003164099,0.000005044572,0.00004486481,0.00003212447,0.0001786488,0.9979721,0.00008166194,0.000007666466,0.000808062],"study_design_scores_gemma":[0.00001263605,0.0001031089,0.01099739,0.00000619602,0.000009996584,0.0001086861,0.000098734,0.004564306,0.9836748,0.0001091347,0.0002998764,0.00001520667],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981118,0.0003789723,0.0009654753,0.00002965663,0.00000430881,0.000008179009,0.00003609044,0.00001078137,0.0004546862],"genre_scores_gemma":[0.9991269,0.000125219,0.0004233676,0.00001735563,0.000001207514,0.000005878491,0.00003629318,0.000008917093,0.0002550447],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001435184,"threshold_uncertainty_score":0.004125834,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008142391380415493,"score_gpt":0.1954147209544136,"score_spread":0.1872723295739981,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}