{"id":"W3046762849","doi":"10.1016/j.pharmthera.2020.107648","title":"TSLP as druggable target – a silver-lining for atopic diseases?","year":2020,"lang":"en","type":"review","venue":"Pharmacology & Therapeutics","topic":"Dermatology and Skin Diseases","field":"Medicine","cited_by":61,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"Svenska Sällskapet för Medicinsk Forskning; Michael Smith Health Research BC","keywords":"Thymic stromal lymphopoietin; Immunology; Atopic dermatitis; Medicine; Immune system; Allergy; Cytokine; Autocrine signalling; Asthma; Paracrine signalling; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001164075,0.0006539653,0.002633766,0.0001735712,0.0002275955,0.00002252044,0.000402765,0.000573219,0.001099841],"category_scores_gemma":[0.00003633947,0.0005557807,0.001120586,0.0002906693,0.0002491078,0.00006426041,0.0001216642,0.0007413452,0.0005166383],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001430865,"about_ca_system_score_gemma":0.001418616,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001262001,"about_ca_topic_score_gemma":1.786563e-7,"domain_scores_codex":[0.9974018,0.000297801,0.0007267407,0.0007052049,0.0001988044,0.0006696626],"domain_scores_gemma":[0.9978192,0.00087171,0.0003862268,0.0003501901,0.0001195606,0.0004531415],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0006909636,0.00114064,0.0005018063,0.03482244,0.01277243,0.001549159,0.0002760679,0.000001715728,0.00001601004,0.000219035,0.1232258,0.8247839],"study_design_scores_gemma":[0.001933833,0.0001842352,0.000007703747,0.0009821616,0.03225999,0.0003300761,0.00002249332,0.0001058092,0.00003283896,0.0004440615,0.9632669,0.0004298694],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00002304644,0.9924617,0.00007717819,0.002064423,0.001571752,0.00244154,0.0003136953,0.0002589025,0.000787775],"genre_scores_gemma":[0.000140626,0.9740374,0.0003657395,0.0212424,0.001076585,0.0009571158,0.0006961942,0.0001469525,0.001336982],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8400411,"threshold_uncertainty_score":0.9998133,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0776112845617467,"score_gpt":0.4264957714524802,"score_spread":0.3488844868907335,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}