{"id":"W3046798142","doi":"10.1002/jnr.24704","title":"Sex differences in kappa opioid receptor antinociception is influenced by the number of X chromosomes in mouse","year":2020,"lang":"en","type":"article","venue":"Journal of Neuroscience Research","topic":"Neuropeptides and Animal Physiology","field":"Neuroscience","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"Women and Children’s Health Research Institute; University of Alberta","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Diabetes and Digestive and Kidney Diseases; National Institute on Drug Abuse; Natural Sciences and Engineering Research Council of Canada","keywords":"κ-opioid receptor; Sexual dimorphism; Context (archaeology); Agonist; Hormone; Gonadal hormones; Internal medicine; Endocrinology; Receptor; Biology; Analgesic; Opioid; Genotype; Gene; Medicine; Pharmacology; Genetics; Castration","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002809404,0.0005315613,0.0003622237,0.001497582,0.0002888944,0.0006358442,0.0004213853,0.0005385749,0.003874117],"category_scores_gemma":[0.0002264197,0.0005216656,0.0005089435,0.0003303183,0.0006503909,0.0004133721,0.0004125865,0.001256996,0.0004835148],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003439542,"about_ca_system_score_gemma":0.000302782,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000700052,"about_ca_topic_score_gemma":0.00192967,"domain_scores_codex":[0.9994884,0.00005693695,0.00006135955,0.0001791824,0.0001199887,0.00009415577],"domain_scores_gemma":[0.9994256,0.00005922772,0.0002677587,0.00005510905,0.00003670896,0.0001556117],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004689263,0.00008727715,0.001242954,0.00003047226,0.00001137733,0.0001129344,0.00006127574,0.00003687752,0.9956762,0.0002451397,0.00004543754,0.001981024],"study_design_scores_gemma":[0.0001388304,0.001363578,0.07340488,0.00005952656,0.0001249106,0.001077548,0.0002467702,0.0007126966,0.9182223,0.000368879,0.004239391,0.00004064674],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9933599,0.001213549,0.002411055,0.0001537269,0.00004334674,0.00003452524,0.001063278,0.00009149591,0.001629156],"genre_scores_gemma":[0.9814145,0.001565344,0.003487931,0.0001840169,0.00002307721,0.0001787949,0.001055116,0.0001395898,0.01195166],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003874117,"threshold_uncertainty_score":0.01296026,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1414225431457063,"score_gpt":0.3907338556894705,"score_spread":0.2493113125437642,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}