{"id":"W3046852139","doi":"10.3390/toxins12080483","title":"Primary Human Derived Blood Outgrowth Endothelial Cells: An Appropriate In Vitro Model to Study Shiga Toxin Mediated Damage of Endothelial Cells","year":2020,"lang":"en","type":"article","venue":"Toxins","topic":"Escherichia coli research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Hospital for Sick Children","funders":"European Rare Kidney Disease Reference Network; Radboud Universitair Medisch Centrum; Canadian Institutes of Health Research; Hospital for Sick Children","keywords":"In vitro; Shiga toxin; Primary (astronomy); Cell biology; Toxin; Biology; Chemistry; Immunology; Microbiology; Biochemistry; Escherichia coli","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005644422,0.0004468006,0.000694229,0.0003084857,0.0002985027,0.0005083937,0.0003856472,0.0005821929,0.001916401],"category_scores_gemma":[0.0002454336,0.0001743176,0.0005001201,0.0004347558,0.0001622179,0.0002761505,0.0003865195,0.001191138,0.001083542],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002190674,"about_ca_system_score_gemma":0.0002154821,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009971728,"about_ca_topic_score_gemma":0.001419571,"domain_scores_codex":[0.9993613,0.0001702092,0.00007363299,0.0001207844,0.0001682213,0.0001058558],"domain_scores_gemma":[0.9996687,0.00008474453,0.00003828518,0.00007755939,0.00008683614,0.00004382415],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005638282,0.000583297,0.001205836,0.0003119354,0.00002968734,0.0005618513,0.0001545625,0.0003136351,0.9921986,0.0003218889,0.0003057761,0.003449006],"study_design_scores_gemma":[0.00007160783,0.004729562,0.01580625,0.00008065694,0.0001357866,0.002787856,0.0002339972,0.002981392,0.9544794,0.0002674247,0.01839712,0.00002907729],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9171007,0.02090508,0.04844996,0.0003980004,0.0006110457,0.000468228,0.003026293,0.0002229408,0.008817735],"genre_scores_gemma":[0.9430897,0.01264632,0.02869417,0.0003152137,0.0001631663,0.0005505563,0.00548637,0.00005390068,0.009000598],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001916401,"threshold_uncertainty_score":0.006411016,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02730390415354571,"score_gpt":0.278307994846704,"score_spread":0.2510040906931583,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}