{"id":"W3046859958","doi":"10.1016/j.jaccao.2020.06.004","title":"Comprehensive Characterization of the Vascular Effects of Cisplatin-Based Chemotherapy in Patients With Testicular Cancer","year":2020,"lang":"en","type":"article","venue":"JACC CardioOncology","topic":"Chemotherapy-induced organ toxicity mitigation","field":"Medicine","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre","funders":"Mason Medical Research Trust; University of Glasgow; British Heart Foundation","keywords":"Medicine; Internal medicine; Testicular cancer; Cisplatin; Cohort; Urology; Chemotherapy; Gastroenterology; Endocrinology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004538556,0.000134693,0.0005480023,0.00005769335,0.0000164089,0.000001907119,0.00008010881,0.0001247754,0.00002179581],"category_scores_gemma":[0.00009825851,0.00009757501,0.0001183262,0.0004473261,0.0001065393,0.00002906036,0.00001649267,0.000147382,8.841928e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001211832,"about_ca_system_score_gemma":0.0001889835,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002256264,"about_ca_topic_score_gemma":0.000003346945,"domain_scores_codex":[0.9990312,0.0001166339,0.0002414571,0.0002035438,0.0002760701,0.0001310347],"domain_scores_gemma":[0.9991033,0.0001214505,0.0002397677,0.0002363601,0.0002478157,0.00005130509],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0003542608,0.0001216079,0.4652475,0.0003378664,0.000124512,0.000002729872,0.0004097771,0.0001856589,0.5313084,0.000001968997,0.00001170643,0.001893959],"study_design_scores_gemma":[0.00587452,0.0004232178,0.6009794,0.000111125,0.00008362449,4.866037e-7,0.000008369604,0.0002150665,0.3920682,9.04924e-7,0.0001814549,0.00005363805],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996424,0.00003765532,0.0003825393,0.001817844,0.00008342362,0.001202509,0.00001161765,0.00001598138,0.00002443583],"genre_scores_gemma":[0.9971575,0.00001189333,0.0002382096,0.002430245,0.00006750346,0.00003115525,0.00003211662,0.0000289551,0.000002384626],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1392402,"threshold_uncertainty_score":0.3978993,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00701745591881764,"score_gpt":0.2193227430665253,"score_spread":0.2123052871477077,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}