{"id":"W3046891294","doi":"10.1111/dom.14160","title":"Effects of glucagon‐like peptide‐1 receptor agonists liraglutide and semaglutide on cardiovascular and renal outcomes across body mass index categories in type 2 diabetes: Results of the <scp>LEADER</scp> and <scp>SUSTAIN</scp> 6 trials","year":2020,"lang":"en","type":"article","venue":"Diabetes Obesity and Metabolism","topic":"Diabetes Treatment and Management","field":"Medicine","cited_by":93,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Lunenfeld-Tanenbaum Research Institute; St. Michael's Hospital","funders":"National Center for Advancing Translational Sciences; National Institute of Diabetes and Digestive and Kidney Diseases; Novo Nordisk","keywords":"Semaglutide; Liraglutide; Medicine; Type 2 diabetes; Dulaglutide; Body mass index; Internal medicine; Lixisenatide; Placebo; Glucagon-like peptide 1 receptor; Overweight; Diabetes mellitus; Myocardial infarction; Glucagon-like peptide-1; Endocrinology; Receptor; Agonist","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005037597,0.0009680018,0.003335936,0.0003666584,0.0003505115,0.001280437,0.0005081667,0.001136503,0.001268075],"category_scores_gemma":[0.004656707,0.0003316417,0.004967482,0.0006207281,0.0005879729,0.0008073762,0.0004462162,0.002159529,0.0001513118],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004081491,"about_ca_system_score_gemma":0.0006022025,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006931964,"about_ca_topic_score_gemma":0.00222957,"domain_scores_codex":[0.9976922,0.001438344,0.0003371292,0.0002303256,0.0001933636,0.000108534],"domain_scores_gemma":[0.9970568,0.001293373,0.0008059097,0.0002363965,0.0002765555,0.0003309394],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.9244609,0.001050103,0.01036636,0.003423277,0.02417632,0.00006347046,0.00009893926,0.0005777202,0.002533433,0.000141408,0.001319037,0.03178904],"study_design_scores_gemma":[0.699053,0.1082397,0.1079395,0.001340349,0.07398579,0.0003051498,0.0003267854,0.001689056,0.002513411,0.001069935,0.003422695,0.0001144748],"study_design_candidate":"meta_analysis","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9384933,0.05626233,0.0004590826,0.0007880706,0.0002989325,0.0004598915,0.001333898,0.00004257714,0.001862023],"genre_scores_gemma":[0.9861773,0.009896722,0.0005753998,0.0007951556,0.0003129169,0.0004310983,0.001267563,0.00001454893,0.0005292608],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005037597,"threshold_uncertainty_score":0.02664167,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01394781384431076,"score_gpt":0.2422442633921924,"score_spread":0.2282964495478817,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}