{"id":"W3046978144","doi":"10.1093/noajnl/vdaa073.030","title":"42. IDENTIFICATION OF BRAIN METASTASIS VULNERABILITIES USING METPLATFORM","year":2020,"lang":"en","type":"article","venue":"Neuro-Oncology Advances","topic":"Redox biology and oxidative stress","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Brain metastasis; Metastasis; Medicine; Autophagy; Cancer research; Cancer; Bioinformatics; Internal medicine; Biology; Apoptosis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002024791,0.0001466458,0.0002660631,0.00003608715,0.00009402807,0.000006145079,0.0002248725,0.0001576645,0.00003127705],"category_scores_gemma":[0.0008316111,0.0001325679,0.00009710182,0.0001248018,0.0003905593,0.0000200055,0.00009833028,0.0001264166,0.00000476139],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009838983,"about_ca_system_score_gemma":0.0000731152,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003754728,"about_ca_topic_score_gemma":0.00001391646,"domain_scores_codex":[0.9987547,0.0002125052,0.0003703556,0.0003937361,0.00008072037,0.0001879535],"domain_scores_gemma":[0.9992049,0.0001491765,0.0002731429,0.0002047312,0.0001039196,0.00006407745],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002199362,0.00004268145,0.002460287,0.00003687125,0.000053762,0.000003370011,0.0001240269,0.0005131969,0.9894204,0.0003267307,0.0003056537,0.006493079],"study_design_scores_gemma":[0.0003672406,0.0007825012,0.0005104654,0.000003079627,0.00003456631,0.00001429386,0.0003835976,0.0001473763,0.9229726,0.0003754583,0.07428308,0.0001257754],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9886499,0.00238496,0.006641984,0.001197237,0.0002882412,0.000188576,0.00007674297,0.00001711289,0.000555221],"genre_scores_gemma":[0.9966987,0.0003748567,0.001496453,0.001122618,0.0001771579,0.0000164912,0.00006718901,0.00001326739,0.00003320497],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07397743,"threshold_uncertainty_score":0.5405963,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03053911386272995,"score_gpt":0.3277943804720643,"score_spread":0.2972552666093344,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}