{"id":"W3047019788","doi":"10.1158/1538-7445.pedca19-a13","title":"Abstract A13: Immunogenomic approaches to optimize immunotherapeutic targeting of neuroblastoma","year":2020,"lang":"en","type":"article","venue":"Cancer Research","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Chimeric antigen receptor; Antigen; Immunotherapy; Medicine; Cancer research; Cancer; Neuroblastoma; Lymphoma; Cancer immunotherapy; Immunology; T cell; Immune system; Internal medicine; Cell culture; Biology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002516701,0.0004231712,0.000266408,0.0003875927,0.0001597175,0.0004055195,0.0002913453,0.0003802891,0.001865477],"category_scores_gemma":[0.0001086993,0.0001687774,0.0003313323,0.0003382445,0.0001599621,0.0002335256,0.0003220602,0.0005569466,0.000643314],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004964912,"about_ca_system_score_gemma":0.0003366757,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004977093,"about_ca_topic_score_gemma":0.0007272977,"domain_scores_codex":[0.9998312,0.00002782134,0.00001341795,0.00003199707,0.00004913169,0.00004639405],"domain_scores_gemma":[0.999948,0.00000668254,0.00001203917,0.000006129413,0.00001507117,0.00001207421],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005402079,0.00008559677,0.0001536947,0.00007332723,0.000007649715,0.00003772079,0.00001496696,0.0009148626,0.9914498,0.0003885245,0.0001690711,0.006650744],"study_design_scores_gemma":[0.00003004631,0.0006527653,0.001269383,0.00001317655,0.00002824361,0.0001646426,0.00001793088,0.002705545,0.9860718,0.0001628721,0.008874179,0.000009483315],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.934787,0.005449201,0.05064546,0.0003204931,0.0001187811,0.0005396632,0.0009564725,0.0003078943,0.006875014],"genre_scores_gemma":[0.9376839,0.003922537,0.05059635,0.0002537683,0.00003813481,0.0003271493,0.000997727,0.00007395558,0.006106528],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001865477,"threshold_uncertainty_score":0.006240666,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.3185861517142442,"score_gpt":0.3984366831874055,"score_spread":0.07985053147316129,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}