{"id":"W3047046898","doi":"10.1158/1538-7445.pedca19-a09","title":"Abstract A09: Glypican-2 targeted CAR T cells designed to effectively eradicate endogenous site density solid tumors in the absence of toxicity","year":2020,"lang":"en","type":"article","venue":"Cancer Research","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Neuroblastoma; In vivo; Cancer research; Antigen; Single-chain variable fragment; In vitro; Pediatric cancer; Biology; Cell culture; Chemistry; Molecular biology; Cancer; Antibody; Immunology; Biochemistry; Monoclonal antibody","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000797469,0.0003788665,0.0001655172,0.0001569028,0.0001201577,0.0003433427,0.0002396533,0.0003873706,0.002665192],"category_scores_gemma":[0.00006103836,0.00009862165,0.0001637112,0.000146274,0.0001459602,0.0001463478,0.0001639367,0.000657528,0.0007941588],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003710857,"about_ca_system_score_gemma":0.0002052669,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007638984,"about_ca_topic_score_gemma":0.0007039248,"domain_scores_codex":[0.9999089,0.000008443801,0.000005595113,0.00002086195,0.00002990489,0.00002629964],"domain_scores_gemma":[0.9999641,0.000003434465,0.000007357049,0.00000335002,0.000007998631,0.00001373437],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001060175,0.000048786,0.0001115952,0.00002139267,0.00000381149,0.00002898635,0.000009106097,0.0001739793,0.9982573,0.0001005452,0.0001666561,0.0009717473],"study_design_scores_gemma":[0.00003445146,0.0004933764,0.001065167,0.000003160827,0.00001524093,0.0002310099,0.00001152316,0.001507532,0.9933994,0.00002411995,0.003211353,0.000003642978],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9911753,0.0003865887,0.004156778,0.00007943494,0.00003007827,0.00008885505,0.0006420674,0.0001355368,0.003305296],"genre_scores_gemma":[0.9883112,0.0002534261,0.004131656,0.00008073778,0.00001048691,0.00007197491,0.001120266,0.00003792232,0.005982283],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002665192,"threshold_uncertainty_score":0.008915961,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1008884823589383,"score_gpt":0.3809940487510608,"score_spread":0.2801055663921225,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}