{"id":"W3047061532","doi":"10.1158/1538-7445.pedca19-b21","title":"Abstract B21: Childhood Cancer Molecular Map (C2M2) to define medulloblastoma heterogeneity and predict treatment response","year":2020,"lang":"en","type":"article","venue":"Cancer Research","topic":"ATP Synthase and ATPases Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medulloblastoma; Biology; Computational biology; Transcriptome; Cancer; Gene; Context (archaeology); Genetics; Bioinformatics; Gene expression","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004516304,0.0002459192,0.0002419144,0.0001016187,0.0002059302,0.00007797002,0.0003438239,0.0001578187,0.0002239382],"category_scores_gemma":[0.0002660092,0.000215831,0.0001041545,0.0002960051,0.0001923619,0.000007455221,0.0004103638,0.0002603778,0.00006773408],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001418454,"about_ca_system_score_gemma":0.0006755285,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005623532,"about_ca_topic_score_gemma":0.0003893668,"domain_scores_codex":[0.9973171,0.0002854297,0.0002175116,0.0008355546,0.0005840485,0.0007604096],"domain_scores_gemma":[0.9984552,0.00006211922,0.00003270026,0.0004534723,0.0002078691,0.0007886747],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002590742,0.000110015,0.003051026,0.00005232978,0.0001752215,0.00009575723,0.0001565626,0.0001502967,0.978457,0.000005256925,0.004273087,0.0108827],"study_design_scores_gemma":[0.000998131,0.001696618,0.01757889,0.00005265374,0.00001426467,0.000003255243,0.00008194089,0.00002726385,0.901104,0.00000707758,0.07820464,0.0002313101],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9822448,0.0073796,0.00005768127,0.009011147,0.00004905411,0.00072294,0.0003865722,0.00002305795,0.0001251733],"genre_scores_gemma":[0.9957074,0.002101527,0.00009264413,0.0007035547,0.0004321258,0.0006209688,0.000044506,0.00005821536,0.0002390907],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07735306,"threshold_uncertainty_score":0.8801335,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0503890329287358,"score_gpt":0.3903681861304564,"score_spread":0.3399791532017206,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}