{"id":"W3047061532","doi":"10.1158/1538-7445.pedca19-b21","title":"Abstract B21: Childhood Cancer Molecular Map (C2M2) to define medulloblastoma heterogeneity and predict treatment response","year":2020,"lang":"en","type":"article","venue":"Cancer Research","topic":"ATP Synthase and ATPases Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medulloblastoma; Biology; Computational biology; Transcriptome; Cancer; Gene; Context (archaeology); Genetics; Bioinformatics; Gene expression","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003468574,0.0003559306,0.0002848319,0.0008918466,0.0002199104,0.000500194,0.000227506,0.0002876258,0.001601669],"category_scores_gemma":[0.0008149065,0.0001129725,0.0002810792,0.0006289387,0.0001640365,0.0001241674,0.0002843165,0.0004019021,0.0002401318],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001194236,"about_ca_system_score_gemma":0.0004290747,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.007213902,"about_ca_topic_score_gemma":0.008071045,"domain_scores_codex":[0.9998498,0.00002458303,0.00000864761,0.00003639582,0.00005825912,0.00002221794],"domain_scores_gemma":[0.9996552,0.00009439178,0.0000796294,0.00003381362,0.00007569259,0.00006126991],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002915651,0.0001951693,0.6899463,0.0002184444,0.0003220229,0.0002923198,0.0001493935,0.03081691,0.2328365,0.0008834692,0.004824664,0.03659913],"study_design_scores_gemma":[0.0001114136,0.0005932138,0.7506142,0.00002347065,0.0002015986,0.0008034537,0.0002180963,0.1047454,0.133455,0.0004964643,0.008702602,0.00003509345],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9891,0.0002204507,0.004588604,0.00009912112,0.00001088732,0.00005675612,0.004388543,0.0001820137,0.00135357],"genre_scores_gemma":[0.9898425,0.00006838152,0.005665231,0.00002558869,0.000003560852,0.00005500388,0.003826169,0.00002559958,0.0004880719],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007213902,"threshold_uncertainty_score":0.0143438,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0503890329287358,"score_gpt":0.3903681861304564,"score_spread":0.3399791532017206,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}