{"id":"W3047086527","doi":"10.4049/jimmunol.1900959","title":"ARID1a Associates with Lymphoid-Restricted Transcription Factors and Has an Essential Role in T Cell Development","year":2020,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Chromatin Remodeling and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Princess Margaret Cancer Centre; University Health Network","funders":"Canadian Institutes of Health Research; Barncancerfonden; Vetenskapsrådet; Knut och Alice Wallenbergs Stiftelse; Cancerfonden","keywords":"Biology; Transcription factor; GATA3; ARID1A; Chromatin remodeling; Chromatin; Progenitor cell; Cell biology; Cellular differentiation; Progenitor; Genetics; Gene; Cancer research; Stem cell; Mutation","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000101814,0.00007934027,0.0001218164,0.00002333791,0.00005376742,0.0000126789,0.0001174332,0.0000760687,0.000005227083],"category_scores_gemma":[0.00001487344,0.00004910711,0.00002104708,0.00004981059,0.00005656767,0.000005373273,0.00001819611,0.0001099183,3.604781e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001926044,"about_ca_system_score_gemma":0.0001541753,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005077108,"about_ca_topic_score_gemma":0.00006212995,"domain_scores_codex":[0.9994731,0.00009249037,0.0001913266,0.00007216867,0.0000653819,0.0001055614],"domain_scores_gemma":[0.9997127,0.00001007954,0.0001389841,0.0000577885,0.00004976738,0.00003070059],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004514868,0.0000391964,0.004204199,0.000004164408,0.00005891882,0.000001672134,0.002057477,0.0003533339,0.9919587,7.835202e-7,0.00001921258,0.000850887],"study_design_scores_gemma":[0.001764785,0.0009832456,0.03961989,0.00001637903,0.00004193528,0.00007328152,0.001984133,0.0002098766,0.9540674,0.00001968968,0.001100537,0.0001188501],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966617,0.002321518,0.0006420228,0.0002732509,0.00004029652,0.00003719991,0.000001263671,0.000002566129,0.00002016535],"genre_scores_gemma":[0.9992657,0.0003591372,0.0002227511,0.00007893017,0.0000477387,5.90574e-7,0.000008017978,0.000007674492,0.000009481503],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03789127,"threshold_uncertainty_score":0.200253,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0109078134181375,"score_gpt":0.2085242319531179,"score_spread":0.1976164185349804,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}