{"id":"W3047086527","doi":"10.4049/jimmunol.1900959","title":"ARID1a Associates with Lymphoid-Restricted Transcription Factors and Has an Essential Role in T Cell Development","year":2020,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Chromatin Remodeling and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Princess Margaret Cancer Centre; University Health Network","funders":"Canadian Institutes of Health Research; Barncancerfonden; Vetenskapsrådet; Knut och Alice Wallenbergs Stiftelse; Cancerfonden","keywords":"Biology; Transcription factor; GATA3; ARID1A; Chromatin remodeling; Chromatin; Progenitor cell; Cell biology; Cellular differentiation; Progenitor; Genetics; Gene; Cancer research; Stem cell; Mutation","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000129194,0.0001897319,0.0001179898,0.00022529,0.0002426417,0.0002392531,0.0001961604,0.0001495063,0.001451371],"category_scores_gemma":[0.0001365052,0.0001499662,0.0001522188,0.0001552476,0.0001685528,0.0001336723,0.0002258725,0.0001551135,0.0006597907],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002287511,"about_ca_system_score_gemma":0.0001372345,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002517164,"about_ca_topic_score_gemma":0.000353964,"domain_scores_codex":[0.9998971,0.00001958146,0.000007147478,0.00003093698,0.0000236889,0.00002151961],"domain_scores_gemma":[0.999874,0.00001384378,0.00004658104,0.00000861744,0.00001008832,0.00004673772],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001071785,0.000006942108,0.00241293,0.00003529275,0.000006765753,0.0001084507,0.00001184363,0.00005442217,0.9957538,0.0001604341,0.00004908649,0.001292839],"study_design_scores_gemma":[0.00002060877,0.0001589913,0.06825557,0.0000151682,0.00002741757,0.001969753,0.00006864921,0.001928796,0.9177174,0.0004444146,0.009384044,0.000009180581],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9895483,0.003246268,0.00505655,0.00007543745,0.00001309366,0.00000868874,0.0003572098,0.0000752243,0.00161912],"genre_scores_gemma":[0.9960726,0.0004034601,0.001560435,0.00002099538,0.000007780577,0.000008494299,0.0004909105,0.00001015035,0.001425035],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001451371,"threshold_uncertainty_score":0.004855335,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0109078134181375,"score_gpt":0.2085242319531179,"score_spread":0.1976164185349804,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}