{"id":"W3047123472","doi":"10.1158/1538-7445.pedca19-a48","title":"Abstract A48: YB-1-based oncolytic virotherapy in combination with CDK4/6-inhibitors against Ewing sarcoma","year":2020,"lang":"en","type":"article","venue":"Cancer Research","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Oncolytic virus; Cancer research; Immune checkpoint; Immune system; Retinoblastoma; Retinoblastoma protein; Viral replication; Biology; Cell cycle; Oncolytic adenovirus; Medicine; Immunotherapy; Virology; Immunology; Cancer; Virus; Internal medicine","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001044512,0.0003180438,0.0004330191,0.0002690607,0.0001065627,0.0002117955,0.0001660269,0.0001692599,0.001150989],"category_scores_gemma":[0.00007912883,0.00008919126,0.0001927717,0.0001510068,0.0001530009,0.000145673,0.0001268009,0.0004054531,0.0002436787],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002581462,"about_ca_system_score_gemma":0.0002226442,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009512442,"about_ca_topic_score_gemma":0.001078581,"domain_scores_codex":[0.9999111,0.00001549743,0.00001027882,0.00001521142,0.00002291023,0.00002510933],"domain_scores_gemma":[0.9999593,0.000007235588,0.000009758933,0.000006672382,0.000004395731,0.00001250259],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0005257232,0.000181417,0.0001905587,0.00006253034,0.00001369578,0.00003600232,0.00001357821,0.0003253719,0.9930128,0.0001066734,0.0001103,0.005421332],"study_design_scores_gemma":[0.00005770609,0.001660722,0.001147778,0.000003797112,0.00002487626,0.0001057955,0.000005463943,0.0008813779,0.9943818,0.0000185424,0.001709183,0.000002991254],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"other","genre_scores_codex":[0.9949897,0.002303271,0.0009310665,0.00005151335,0.00004632049,0.0000533017,0.000218993,0.00008714946,0.001318574],"genre_scores_gemma":[0.9968885,0.0006716577,0.001037142,0.0000122346,0.00001381361,0.00002549846,0.0001888938,0.00001186143,0.001150481],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.001150989,"threshold_uncertainty_score":0.00385046,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09914652753803432,"score_gpt":0.4084362448651844,"score_spread":0.30928971732715,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}