{"id":"W3047136940","doi":"10.1016/j.tox.2020.152546","title":"The impact of sex on hepatotoxic, inflammatory and proliferative responses in mouse models of liver carcinogenesis","year":2020,"lang":"en","type":"article","venue":"Toxicology","topic":"Liver Disease Diagnosis and Treatment","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":false,"ca_institutions":"Canada Research Chairs; University of Toronto; University of New Brunswick","funders":"Canadian Institutes of Health Research","keywords":"Inflammation; Liver cancer; Carcinogenesis; Carcinogen; Cancer; Medicine; Internal medicine; Endocrinology; Hepatocellular carcinoma; Hepatocyte; Genetically modified mouse; Physiology; Immunology; Biology; Transgene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004184527,0.0007272165,0.0004443715,0.001945814,0.0003693323,0.0006528824,0.0003080316,0.0006218663,0.002421696],"category_scores_gemma":[0.0002709747,0.0002984682,0.0005329456,0.0005372354,0.0006396369,0.0005456632,0.0002671548,0.001137624,0.0003429786],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003715623,"about_ca_system_score_gemma":0.000408146,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009484605,"about_ca_topic_score_gemma":0.002080563,"domain_scores_codex":[0.9994606,0.0001282366,0.00003943805,0.00008860396,0.0001538034,0.0001293079],"domain_scores_gemma":[0.9995245,0.00006894629,0.0001268696,0.00005626567,0.00005489669,0.0001685552],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.007451916,0.0007887721,0.004829387,0.00009118339,0.00004473727,0.0002298166,0.0001205003,0.0002044123,0.9786275,0.0003687179,0.0001581754,0.007085057],"study_design_scores_gemma":[0.0001585381,0.007489562,0.03166387,0.00003875884,0.0001927117,0.0004643503,0.0003778824,0.0009253963,0.9548805,0.0004554432,0.003314409,0.00003861474],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9919239,0.003218084,0.001471265,0.0002670433,0.0001028653,0.00004432131,0.00101156,0.00008209232,0.001878926],"genre_scores_gemma":[0.985516,0.002712895,0.001379057,0.0001684866,0.00003846174,0.00009658589,0.0006735738,0.00005786061,0.009357049],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002421696,"threshold_uncertainty_score":0.008101404,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04259095814969067,"score_gpt":0.3018122501325592,"score_spread":0.2592212919828685,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}