{"id":"W3047325596","doi":"10.1038/s41586-020-2564-6","title":"Mucosal or systemic microbiota exposures shape the B cell repertoire","year":2020,"lang":"en","type":"article","venue":"Nature","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":197,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University Medical Centre","funders":"","keywords":"Antibody Repertoire; Biology; Repertoire; Antibody; Immunology; Microbiome; Antigen; B cell; Microbiology; Immunoglobulin G; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002142699,0.0001994376,0.0003083063,0.000289904,0.0002305425,0.001266968,0.000183973,0.0004918632,0.00685113],"category_scores_gemma":[0.000395378,0.0002360748,0.0002192557,0.0001723515,0.0003995506,0.000557163,0.0005000808,0.0009105921,0.002309552],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002520512,"about_ca_system_score_gemma":0.0001980754,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003154528,"about_ca_topic_score_gemma":0.0007530083,"domain_scores_codex":[0.9997119,0.00005344166,0.000007609465,0.00006967295,0.00005493511,0.0001023212],"domain_scores_gemma":[0.9998098,0.00004027536,0.00003467946,0.00002426374,0.0000202632,0.00007071749],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009048403,0.00006697351,0.01818784,0.0001507361,0.00003941152,0.0002290982,0.0002101586,0.0002558826,0.935801,0.001246317,0.001999615,0.0409082],"study_design_scores_gemma":[0.0003183011,0.001960517,0.6384653,0.0003822587,0.0002741113,0.003011585,0.004104898,0.005388634,0.2750498,0.01453735,0.05640699,0.0001001319],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9729289,0.006784376,0.002988117,0.0007315433,0.0002261476,0.00001662711,0.0006263309,0.0001643171,0.01553357],"genre_scores_gemma":[0.9926482,0.001828986,0.001021986,0.0004714176,0.00009217479,0.00001473752,0.0002168428,0.00007006353,0.003635509],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00685113,"threshold_uncertainty_score":0.02291936,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009959829672597375,"score_gpt":0.2144606486022058,"score_spread":0.2045008189296084,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}