{"id":"W3047325596","doi":"10.1038/s41586-020-2564-6","title":"Mucosal or systemic microbiota exposures shape the B cell repertoire","year":2020,"lang":"en","type":"article","venue":"Nature","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":197,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University Medical Centre","funders":"","keywords":"Antibody Repertoire; Biology; Repertoire; Antibody; Immunology; Microbiome; Antigen; B cell; Microbiology; Immunoglobulin G; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["research_integrity","insufficient_payload"],"consensus_categories":["research_integrity","insufficient_payload"],"category_scores_codex":[0.0001316107,0.0002902988,0.0003566635,0.00004121192,0.0003624732,0.00003044299,0.0007958282,0.002501639,0.001710912],"category_scores_gemma":[0.0001139009,0.0001615426,0.000162293,0.0002346463,0.0002564526,0.00005699924,0.0002248221,0.003546399,0.001827672],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000275212,"about_ca_system_score_gemma":0.0001080769,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002119894,"about_ca_topic_score_gemma":0.00001427711,"domain_scores_codex":[0.9984006,0.0002737121,0.0003232975,0.0004907041,0.0000433046,0.000468434],"domain_scores_gemma":[0.9990805,0.0001933094,0.0001467475,0.0004687091,0.00007885029,0.00003186441],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003359667,0.00005693124,0.0002566099,0.00005579743,0.00009837384,0.00003909513,0.0006534117,9.736999e-7,0.8498341,0.0001294372,0.1474891,0.001050192],"study_design_scores_gemma":[0.001339407,0.0002804156,0.0001810643,0.00003346024,0.00006742514,0.0005656283,0.000756309,0.000006021801,0.5586305,0.00001157162,0.4378705,0.000257748],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9140881,0.0682392,0.000008101962,0.01171571,0.002337675,0.0004627326,0.00007855216,0.0002775935,0.002792278],"genre_scores_gemma":[0.9798195,0.0002980989,0.0000314131,0.007448862,0.0001887334,0.00001722598,0.0001012559,0.00003301537,0.01206192],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2912036,"threshold_uncertainty_score":0.9992017,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009959829672597375,"score_gpt":0.2144606486022058,"score_spread":0.2045008189296084,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}