{"id":"W3047362268","doi":"10.1158/1538-7445.pedca19-b06","title":"Abstract B06: Candidate differentiation stall in epithelial mesenchymal transition in H3K27M diffuse midline glioma","year":2020,"lang":"en","type":"article","venue":"Cancer Research","topic":"Cancer-related molecular mechanisms research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Carcinogenesis; Glioma; Biology; Epithelial–mesenchymal transition; Cancer research; Gene; Pathology; Medicine; Transition (genetics); Genetics","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009316609,0.0001702218,0.0002378243,0.0003983475,0.0002755716,0.0002542781,0.0001065544,0.0002114912,0.001672152],"category_scores_gemma":[0.0001663075,0.0001110298,0.0002363494,0.0003593762,0.0001595344,0.00009623868,0.0002121562,0.0002701964,0.0005788542],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003552522,"about_ca_system_score_gemma":0.0002642419,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002100395,"about_ca_topic_score_gemma":0.003200113,"domain_scores_codex":[0.9999194,0.000005016766,0.00000469609,0.00002635078,0.00002527652,0.00001925704],"domain_scores_gemma":[0.9998354,0.00001815567,0.00006429904,0.00001081062,0.00002531516,0.00004607247],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000376845,0.00001819384,0.01813371,0.00009521886,0.00002353389,0.0004034384,0.00005143294,0.0003225027,0.9766256,0.0001289502,0.0003037018,0.003516836],"study_design_scores_gemma":[0.00002271148,0.0003956548,0.4599811,0.0000285121,0.00008008022,0.002108651,0.0003440316,0.004800838,0.5247445,0.0003746545,0.007090698,0.00002852142],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946405,0.0007458515,0.001972173,0.0000485057,0.00001622201,0.00001380247,0.001808401,0.0001043033,0.0006501175],"genre_scores_gemma":[0.9948639,0.0002619832,0.001578703,0.00005944388,0.000005726317,0.0000183474,0.002137027,0.00003665928,0.001038234],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002100395,"threshold_uncertainty_score":0.005593896,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03525198345392552,"score_gpt":0.3475909443353531,"score_spread":0.3123389608814277,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}