{"id":"W3047381658","doi":"10.1016/j.jacbts.2020.06.008","title":"Glycation and Serum Albumin Infiltration Contribute to the Structural Degeneration of Bioprosthetic Heart Valves","year":2020,"lang":"en","type":"article","venue":"JACC Basic to Translational Science","topic":"Cardiovascular Function and Risk Factors","field":"Medicine","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Heart, Lung, and Blood Institute; National Institutes of Health","keywords":"Glycation; Albumin; Infiltration (HVAC); Degeneration (medical); Fibrinogen; Internal medicine; Chemistry; Medicine; Pathology; Receptor; Materials science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004957965,0.0004777978,0.0002754605,0.0004559959,0.0001734278,0.0007214834,0.0002061349,0.0005624021,0.001007272],"category_scores_gemma":[0.0004736732,0.0001741877,0.0003223935,0.0002411456,0.0004320522,0.0003085216,0.0005633858,0.0006688216,0.0002127051],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001962683,"about_ca_system_score_gemma":0.000256203,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002695748,"about_ca_topic_score_gemma":0.0003040084,"domain_scores_codex":[0.9997324,0.00007072955,0.00002473567,0.00005473099,0.00006471337,0.00005262033],"domain_scores_gemma":[0.9996039,0.00003392253,0.0001930079,0.00004155396,0.00004894269,0.00007855998],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003667942,0.0006295267,0.1655512,0.0006418479,0.0004052025,0.002685562,0.0004227902,0.0004130447,0.7289638,0.004070268,0.002122295,0.09042647],"study_design_scores_gemma":[0.000126993,0.001724882,0.890137,0.00009630265,0.0003477062,0.007460352,0.0003627171,0.002527582,0.08134828,0.005745845,0.01007182,0.00005055717],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.967947,0.02103701,0.005071057,0.001421389,0.0002427392,0.00004444323,0.0002085661,0.00008562245,0.003942148],"genre_scores_gemma":[0.9934656,0.003459504,0.001200892,0.0002044451,0.0001669258,0.00001010416,0.00008153768,0.000006915688,0.001404057],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001007272,"threshold_uncertainty_score":0.003369629,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01672596170918723,"score_gpt":0.264131738259233,"score_spread":0.2474057765500458,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}