{"id":"W3047405871","doi":"10.1158/1538-7445.pedca19-a62","title":"Abstract A62: A cerebral organoid model of pediatric glioma","year":2020,"lang":"en","type":"article","venue":"Cancer Research","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"ATRX; Organoid; Biology; Epigenetics; Induced pluripotent stem cell; Cancer research; Embryonic stem cell; Glioma; Cancer; Brain tumor; Pathology; Cell biology; Medicine; Mutation; Genetics; Gene","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002686626,0.0005077512,0.0003052884,0.0006320146,0.0002655706,0.0004109557,0.000457561,0.0006282924,0.002420579],"category_scores_gemma":[0.00008743285,0.0002314769,0.0004304549,0.0003598433,0.0003367612,0.0002877926,0.0003530752,0.001287761,0.0008149508],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005717687,"about_ca_system_score_gemma":0.0005847625,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002585229,"about_ca_topic_score_gemma":0.002739787,"domain_scores_codex":[0.9997788,0.0000255102,0.00001753307,0.00005490092,0.00008450907,0.00003878987],"domain_scores_gemma":[0.9998447,0.00002224059,0.0000354588,0.00002541181,0.00001628616,0.00005588395],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002404182,0.0001750849,0.0002301173,0.00008794036,0.00001281909,0.0005435613,0.00009733722,0.0008125026,0.9939458,0.0009923899,0.0004366493,0.002425391],"study_design_scores_gemma":[0.00007446214,0.001585444,0.002317529,0.00002554211,0.00003693054,0.00143125,0.0001521144,0.003237395,0.9762425,0.0002565765,0.01461927,0.00002092802],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9613751,0.001811519,0.02068484,0.000390921,0.0002490746,0.0005025365,0.006095202,0.0005450157,0.008345894],"genre_scores_gemma":[0.9752749,0.001412132,0.01143559,0.00009994458,0.00001546157,0.0003842072,0.002605201,0.00009513905,0.008677269],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002585229,"threshold_uncertainty_score":0.008097649,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0812892223524317,"score_gpt":0.3641801249010659,"score_spread":0.2828909025486342,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}