{"id":"W3047511740","doi":"10.1186/s13148-020-00909-2","title":"Epigenetic age and pregnancy outcomes: GrimAge acceleration is associated with shorter gestational length and lower birthweight","year":2020,"lang":"en","type":"article","venue":"Clinical Epigenetics","topic":"Birth, Development, and Health","field":"Medicine","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"Athabasca University; University of Calgary","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Center for Advancing Translational Sciences; National Center for Research Resources; National Institutes of Health","keywords":"dNaM; Gestational age; Medicine; Pregnancy; Body mass index; Obstetrics; Birth weight; Gestation; Epigenetics; DNA methylation; Internal medicine; Biology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002513052,0.0002350049,0.0005741196,0.00004267625,0.000120917,0.0000486454,0.00006952877,0.0002361547,0.0001338712],"category_scores_gemma":[0.0004248822,0.0001800556,0.00006548156,0.0001422827,0.0002520504,0.00005767206,0.00005818386,0.0003922116,0.00001872827],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002611967,"about_ca_system_score_gemma":0.0002776022,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004816025,"about_ca_topic_score_gemma":0.00004872169,"domain_scores_codex":[0.9979649,0.00009849742,0.0007609177,0.0005348013,0.0003329421,0.0003079642],"domain_scores_gemma":[0.9985725,0.0003499647,0.0001857748,0.0001955416,0.0001556528,0.0005405842],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00008944483,0.0003050062,0.9808134,0.0001429577,0.0001887043,0.0001557899,0.001069723,0.000001395595,0.00006751587,0.0006223308,0.0004572543,0.0160865],"study_design_scores_gemma":[0.002576197,0.001356652,0.993036,0.0002109725,0.0001454906,0.000003541905,0.00004787545,0.0005324081,0.000089478,0.0012493,0.0005241833,0.0002278622],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9896498,0.0009896568,0.001803406,0.005690448,0.0001411038,0.0006298191,0.00004253547,0.00006521674,0.0009879743],"genre_scores_gemma":[0.9541527,0.02794707,0.005829525,0.01169497,0.0001074618,0.00001208299,0.00008078365,0.00004302752,0.0001324013],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03549716,"threshold_uncertainty_score":0.7342453,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09456844817985295,"score_gpt":0.3593381486358895,"score_spread":0.2647697004560366,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}