{"id":"W3047511740","doi":"10.1186/s13148-020-00909-2","title":"Epigenetic age and pregnancy outcomes: GrimAge acceleration is associated with shorter gestational length and lower birthweight","year":2020,"lang":"en","type":"article","venue":"Clinical Epigenetics","topic":"Birth, Development, and Health","field":"Medicine","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"Athabasca University; University of Calgary","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Center for Advancing Translational Sciences; National Center for Research Resources; National Institutes of Health","keywords":"dNaM; Gestational age; Medicine; Pregnancy; Body mass index; Obstetrics; Birth weight; Gestation; Epigenetics; DNA methylation; Internal medicine; Biology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004338512,0.0001970174,0.0001757312,0.0003040521,0.0001219015,0.0003587534,0.0002494134,0.0002395459,0.002227891],"category_scores_gemma":[0.002538845,0.0001269378,0.0002790749,0.0003757667,0.00018185,0.0001469062,0.0002600009,0.000431114,0.0001382252],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001660032,"about_ca_system_score_gemma":0.0002596759,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003814668,"about_ca_topic_score_gemma":0.002903025,"domain_scores_codex":[0.9998065,0.00006303594,0.00001362686,0.00005786898,0.00003099731,0.00002803805],"domain_scores_gemma":[0.9981059,0.0004176688,0.001048721,0.0001398875,0.00009131354,0.0001965946],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001725854,0.00001278731,0.9972289,0.000008606759,0.0000536577,0.00004300307,0.00002693079,0.00003365539,0.0006296966,0.00002047015,0.00003895373,0.00173063],"study_design_scores_gemma":[0.000001603697,0.00003778433,0.9994666,0.000003102325,0.00002014318,0.00008838413,0.0000203155,0.0001158677,0.0001352861,0.00002295219,0.00008682281,0.000001067126],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985042,0.0005071035,0.00017114,0.00009190512,0.000005923011,0.000002888212,0.0002279251,0.000005785136,0.0004831647],"genre_scores_gemma":[0.9994129,0.0001333414,0.000126643,0.00001625591,0.000006593727,0.000002668353,0.0001032909,0.000001817113,0.0001965424],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003814668,"threshold_uncertainty_score":0.007584929,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09456844817985295,"score_gpt":0.3593381486358895,"score_spread":0.2647697004560366,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}