{"id":"W3047577120","doi":"10.1021/acsomega.0c02310","title":"Synthesis of the Novel AT<sub>1</sub> Receptor Tracer [<sup>18</sup>F]Fluoropyridine–Candesartan via Click Chemistry","year":2020,"lang":"en","type":"article","venue":"ACS Omega","topic":"Click Chemistry and Applications","field":"Chemistry","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Centre Hospitalier de l’Université de Montréal","funders":"Canadian Institutes of Health Research","keywords":"Candesartan; Chemistry; Imidazole; Trifluoroacetic acid; Medicinal chemistry; Nuclear chemistry; Angiotensin II; Organic chemistry; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002342984,0.0004784291,0.0002969427,0.0002604942,0.0001597761,0.0003481096,0.0005673054,0.0004242104,0.004992213],"category_scores_gemma":[0.0001644573,0.0003314322,0.0002081592,0.0001594059,0.000194982,0.0003835175,0.0002096355,0.0005056033,0.001824948],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003559464,"about_ca_system_score_gemma":0.0002516909,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005576076,"about_ca_topic_score_gemma":0.0009817277,"domain_scores_codex":[0.9998904,0.000009066885,0.000004146817,0.00003671098,0.00003266253,0.00002697808],"domain_scores_gemma":[0.9999144,0.0000160572,0.00002032445,0.000008910395,0.00001449846,0.00002570136],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005457837,0.00001003941,0.00004422547,0.00003483162,0.000005349556,0.0001194935,0.00001135323,0.000110825,0.9959373,0.0003097801,0.0003224526,0.003039649],"study_design_scores_gemma":[0.00001910268,0.0001509344,0.0005645758,0.00000282007,0.00001234322,0.0003346195,0.000006983143,0.001171709,0.991305,0.00005244625,0.006369746,0.000009773512],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.808428,0.004581115,0.1510598,0.0006396337,0.0002405619,0.0004061622,0.002242805,0.003864712,0.0285372],"genre_scores_gemma":[0.8761818,0.002779781,0.09149559,0.0002608725,0.0001240765,0.0003325977,0.002038597,0.0003044175,0.02648222],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004992213,"threshold_uncertainty_score":0.01670063,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01920452761519285,"score_gpt":0.2257337631779945,"score_spread":0.2065292355628017,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}