{"id":"W3047577120","doi":"10.1021/acsomega.0c02310","title":"Synthesis of the Novel AT<sub>1</sub> Receptor Tracer [<sup>18</sup>F]Fluoropyridine–Candesartan via Click Chemistry","year":2020,"lang":"en","type":"article","venue":"ACS Omega","topic":"Click Chemistry and Applications","field":"Chemistry","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Centre Hospitalier de l’Université de Montréal","funders":"Canadian Institutes of Health Research","keywords":"Candesartan; Chemistry; Imidazole; Trifluoroacetic acid; Medicinal chemistry; Nuclear chemistry; Angiotensin II; Organic chemistry; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001111349,0.0003804577,0.0004361109,0.00001121075,0.0002330255,0.00003416514,0.0008930689,0.0003445511,0.001115791],"category_scores_gemma":[0.0004816733,0.0003325536,0.0003245381,0.0004153042,0.0002682506,0.00008992252,0.0003397778,0.0004724761,0.0001339153],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001449803,"about_ca_system_score_gemma":0.00009172829,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001289366,"about_ca_topic_score_gemma":0.000001832521,"domain_scores_codex":[0.9978728,0.00001446929,0.0006036138,0.0006486329,0.0004209655,0.0004394865],"domain_scores_gemma":[0.9978863,0.0003511263,0.0003323124,0.001033786,0.0001111956,0.0002852998],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000641338,0.0001999111,0.0006719616,0.0003485751,0.00009829267,0.000001146582,0.0002242413,0.00007707356,0.9829798,0.00002366073,0.01363787,0.001673348],"study_design_scores_gemma":[0.0004682123,0.000005880899,0.00007053283,0.0000796432,0.0001102729,0.00001620609,0.0001839572,0.0004615251,0.9574994,0.0000256163,0.04072489,0.0003538698],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9746743,0.0001162216,0.00003062359,0.003299972,0.00002209081,0.0001446185,0.0004620585,0.0001438618,0.02110622],"genre_scores_gemma":[0.9969767,0.00006154388,0.0001064088,0.0003342555,0.0005394397,0.0001795433,0.00007891026,0.00007191281,0.001651305],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02708703,"threshold_uncertainty_score":0.9999127,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01920452761519285,"score_gpt":0.2257337631779945,"score_spread":0.2065292355628017,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}