{"id":"W3047592794","doi":"10.1158/1538-7445.pedca19-ia13","title":"Abstract IA13: Molecular targeted therapies and precision medicine for children with neuroblastoma and other refractory malignancies","year":2020,"lang":"en","type":"article","venue":"Cancer Research","topic":"Neuroblastoma Research and Treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Neuroblastoma; Medicine; Cancer research; Panobinostat; Pediatric cancer; Cancer; Targeted therapy; Pharmacology; Oncology; Histone; Internal medicine; Biology; Histone deacetylase","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003206515,0.0002810811,0.0003185293,0.0003466245,0.000169243,0.0003876023,0.00030545,0.0003806264,0.003372744],"category_scores_gemma":[0.0001645535,0.00008186021,0.0003176614,0.0003175482,0.0002203831,0.0002178525,0.0003628084,0.0007384796,0.0007793932],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009726621,"about_ca_system_score_gemma":0.00101824,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001882293,"about_ca_topic_score_gemma":0.003861389,"domain_scores_codex":[0.9999229,0.00001564603,0.000006614347,0.00001341442,0.00002249057,0.00001896802],"domain_scores_gemma":[0.9999014,0.00001290988,0.00003155798,0.000006964646,0.00001741592,0.00002976987],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.003119893,0.0005666511,0.01540802,0.001999232,0.0002854536,0.002067025,0.0001111453,0.002157395,0.186545,0.007520493,0.04121125,0.7390084],"study_design_scores_gemma":[0.002720319,0.01062713,0.07425811,0.001249476,0.0006789623,0.01994137,0.0001939406,0.005785311,0.2465714,0.003786066,0.6340687,0.0001191986],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.4312713,0.4700899,0.02377892,0.01527635,0.001385128,0.0005954723,0.004576427,0.001367419,0.05165908],"genre_scores_gemma":[0.8158028,0.1307975,0.02499907,0.004100283,0.0005556458,0.0004033003,0.003475196,0.00009995518,0.01976622],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.003372744,"threshold_uncertainty_score":0.01128298,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06004006402092738,"score_gpt":0.3746137212664933,"score_spread":0.3145736572455659,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}