{"id":"W3047610650","doi":"10.1261/rna.074336.119","title":"αβDCA method identifies unspecific binding but specific disruption of the group I intron by the StpA chaperone","year":2020,"lang":"en","type":"article","venue":"RNA","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université du Québec à Montréal","funders":"Natural Sciences and Engineering Research Council of Canada; Institute for Basic Science; Ministry of Education, Science and Technology","keywords":"Biology; Intron; Chaperone (clinical); Genetics; Computational biology; Group II intron; Gene; RNA; RNA splicing","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003109232,0.0001257761,0.0001298049,0.00001186104,0.000143219,0.00003659551,0.0003759775,0.00009141867,0.00008520415],"category_scores_gemma":[0.00005462197,0.00007634926,0.0001182429,0.0001082084,0.00007603386,0.00000511177,0.0001392767,0.00009295851,0.00002191811],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009462278,"about_ca_system_score_gemma":0.00001043424,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001114977,"about_ca_topic_score_gemma":0.000003413463,"domain_scores_codex":[0.9989893,0.0001947509,0.0002006671,0.0002701523,0.000180943,0.0001641177],"domain_scores_gemma":[0.999414,0.00002434907,0.0001350694,0.0003572605,0.00002674286,0.00004263233],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004782556,0.00001562915,0.00003176804,0.00001392811,0.0000267836,3.407293e-7,0.0001288266,0.000005865577,0.9857552,0.000665846,0.002108499,0.0111995],"study_design_scores_gemma":[0.0001246806,0.00009393717,0.000196872,0.0000133673,0.0000161488,0.000003021599,0.00041972,0.00002442422,0.9586688,0.0001592963,0.04018277,0.00009698112],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9562595,0.002585263,0.03723856,0.002494479,0.0003871112,0.0003566388,0.00005501184,0.00001418165,0.0006092151],"genre_scores_gemma":[0.9975502,0.0004611302,0.0007220344,0.0001730731,0.0003493882,0.00001965588,0.00003135351,0.00002073333,0.0006724045],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04129069,"threshold_uncertainty_score":0.3113433,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01920060990870116,"score_gpt":0.2464448654299587,"score_spread":0.2272442555212576,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}