{"id":"W3047647508","doi":"10.18502/jovr.v15i3.7457","title":"Ocular Gene Therapy with Adeno-associated Virus Vectors: Current Outlook for Patients and Researchers","year":2020,"lang":"en","type":"review","venue":"Journal of Ophthalmic and Vision Research","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Medicine; Adeno-associated virus; Genetic enhancement; Clinical trial; Intensive care medicine; Disappointment; Bioinformatics; Vector (molecular biology); Pathology; Gene; Psychotherapist","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001552701,0.0008258644,0.001025148,0.001380314,0.0004073369,0.00146218,0.0008533855,0.002140621,0.003919248],"category_scores_gemma":[0.001552934,0.0002199957,0.0004931937,0.001313108,0.0008747281,0.003818762,0.0008253626,0.004215444,0.002245662],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007773619,"about_ca_system_score_gemma":0.001147848,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00078269,"about_ca_topic_score_gemma":0.001439139,"domain_scores_codex":[0.9996656,0.00008317494,0.00004122126,0.00004773594,0.0001253977,0.00003692133],"domain_scores_gemma":[0.9991881,0.0004646191,0.00005840519,0.00002188307,0.0001888488,0.00007815508],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008751731,0.00008933651,0.0001153923,0.007144273,0.00003494793,0.0001962239,0.0001162738,0.000263604,0.001364722,0.0127751,0.133897,0.8439157],"study_design_scores_gemma":[0.00001180231,0.00007716679,0.0001321904,0.001832705,0.00002080759,0.0005174328,0.00006873693,0.00004665198,0.0001673733,0.003551462,0.993561,0.00001275895],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00005921307,0.9949195,0.0001503497,0.002553994,0.001209807,0.000002592605,0.000008848763,0.00001123926,0.001084415],"genre_scores_gemma":[0.0004275276,0.9950593,0.0003085306,0.002146952,0.001069578,0.000008556649,0.00002197331,0.0000040469,0.0009537392],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003919248,"threshold_uncertainty_score":0.01311117,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.151255700653105,"score_gpt":0.4878219063627907,"score_spread":0.3365662057096857,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}