{"id":"W3047647508","doi":"10.18502/jovr.v15i3.7457","title":"Ocular Gene Therapy with Adeno-associated Virus Vectors: Current Outlook for Patients and Researchers","year":2020,"lang":"en","type":"review","venue":"Journal of Ophthalmic and Vision Research","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Medicine; Adeno-associated virus; Genetic enhancement; Clinical trial; Intensive care medicine; Disappointment; Bioinformatics; Vector (molecular biology); Pathology; Gene; Psychotherapist","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.003123919,0.000411695,0.001133696,0.000480727,0.0002839197,0.0001890317,0.0006404391,0.0004080851,0.00002328444],"category_scores_gemma":[0.0007133693,0.0002748262,0.0003435175,0.0004570677,0.0003697849,0.00001749603,0.0003312911,0.001347286,0.000004660308],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001350505,"about_ca_system_score_gemma":0.001221658,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008044351,"about_ca_topic_score_gemma":0.00000339364,"domain_scores_codex":[0.9952435,0.001327633,0.0007107845,0.000631964,0.001387122,0.0006989319],"domain_scores_gemma":[0.9969348,0.0003293325,0.0004368984,0.0003501743,0.001377189,0.0005716487],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.005204637,0.0005265323,0.0001381991,0.001582767,0.0008966603,0.00007013706,0.0000656421,5.792963e-7,0.001982647,0.000001365023,0.002752694,0.9867781],"study_design_scores_gemma":[0.003519863,0.04268049,0.00007015575,0.002686577,0.0001042015,0.0001326721,0.00004069788,0.00001300326,0.001045294,0.00003337244,0.9492786,0.0003950822],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.07142846,0.9268555,0.00001456636,0.00009019077,0.00007615276,0.001386644,0.0001212152,0.000003297866,0.00002395495],"genre_scores_gemma":[0.003996583,0.9950491,0.0001028131,0.00001482708,0.0003689591,0.00006900225,0.0001380925,0.0001103395,0.0001502633],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9863831,"threshold_uncertainty_score":0.9999704,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.151255700653105,"score_gpt":0.4878219063627907,"score_spread":0.3365662057096857,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}