{"id":"W3047662744","doi":"10.1093/nar/gkaa652","title":"LOTUS domain is a novel class of G-rich and G-quadruplex RNA binding domain","year":2020,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"Viral Infections and Immunology Research","field":"Medicine","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"Structural Genomics Consortium; University of Toronto","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of General Medical Sciences; Fundamental Research Funds for the Central Universities; National Institutes of Health; AgBioResearch, Michigan State University","keywords":"Biology; Lotus; Computational biology; G-quadruplex; Domain (mathematical analysis); RNA; Genetics; DNA; Molecular biology; Gene; Botany","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006079374,0.0003735281,0.0003446671,0.0006334794,0.0003770787,0.0003614108,0.0003047931,0.000293728,0.001732416],"category_scores_gemma":[0.0001262009,0.0001549156,0.0003240636,0.0004917699,0.0002713809,0.000369323,0.0004195205,0.000319828,0.0008153322],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003126117,"about_ca_system_score_gemma":0.0002018217,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003599601,"about_ca_topic_score_gemma":0.0004152281,"domain_scores_codex":[0.9999255,0.000006706765,0.000004782954,0.00002471592,0.00002256122,0.00001572341],"domain_scores_gemma":[0.9999213,0.0000085478,0.0000257254,0.000005700289,0.00000714808,0.00003156586],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004502975,0.00005901548,0.006341465,0.0002600522,0.000041634,0.001228585,0.00008460401,0.0003800395,0.9672445,0.001057783,0.001461117,0.02139096],"study_design_scores_gemma":[0.0001375498,0.001078688,0.1132776,0.00008339096,0.0001512361,0.02659456,0.0002253281,0.008373152,0.6849945,0.002523008,0.1624367,0.0001243181],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9648425,0.008690118,0.01617092,0.0002005677,0.00007054293,0.0001081803,0.003044707,0.0008978232,0.005974595],"genre_scores_gemma":[0.9736338,0.001577444,0.01193613,0.000290224,0.00004385502,0.00009807236,0.006192589,0.00006932229,0.006158442],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001732416,"threshold_uncertainty_score":0.005795479,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09224719540852021,"score_gpt":0.3772705584595958,"score_spread":0.2850233630510756,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}