{"id":"W3047784998","doi":"10.1016/j.stem.2020.07.004","title":"Universal Stem Cells: Making the Unsafe Safe","year":2020,"lang":"en","type":"letter","venue":"Cell stem cell","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"Canadian Institutes of Health Research","keywords":"Induced pluripotent stem cell; Stem cell; Scopus; Biology; Transplantation; Immune system; Immunology; Cancer research; Medicine; Embryonic stem cell; MEDLINE; Cell biology; Internal medicine; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003749636,0.000583022,0.0006443506,0.0002969874,0.002472907,0.002970212,0.001094009,0.02684321,0.004570054],"category_scores_gemma":[0.009566643,0.0003776023,0.0006756551,0.0002128078,0.004961669,0.003904113,0.002029903,0.02045007,0.002702908],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002098289,"about_ca_system_score_gemma":0.001885596,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001547408,"about_ca_topic_score_gemma":0.00289668,"domain_scores_codex":[0.9973941,0.0005866153,0.0001544184,0.0002663118,0.001261535,0.0003370496],"domain_scores_gemma":[0.9960026,0.002698612,0.0001880262,0.0001955367,0.0004840276,0.0004310269],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001240004,0.0000695162,0.0003621647,0.0001071891,0.0000273189,0.001081281,0.0002884836,0.0001522083,0.002944377,0.07000295,0.8801394,0.04470107],"study_design_scores_gemma":[0.0000702497,0.00007253491,0.0002176503,0.00005928415,0.00001336725,0.0005401877,0.0002509118,0.000326299,0.002368639,0.06337994,0.9326699,0.00003089709],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.001131884,0.007238069,0.001810355,0.9562078,0.02319294,0.00001914554,0.00005550257,0.00005942988,0.01028491],"genre_scores_gemma":[0.02336936,0.005828979,0.002255733,0.9093705,0.02042182,0.00009271655,0.00005518545,0.00006671699,0.03853912],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.02684321,"threshold_uncertainty_score":0.01983023,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01951225861638796,"score_gpt":0.2302212009821811,"score_spread":0.2107089423657932,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}