{"id":"W3048040415","doi":"10.1002/cncr.33071","title":"A phase 2 trial of buparlisib in patients with platinum‐resistant metastatic urothelial carcinoma","year":2020,"lang":"en","type":"article","venue":"Cancer","topic":"Bladder and Urothelial Cancer Treatments","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"National Cancer Institute; NIH Clinical Center; Bladder Cancer Advocacy Network","keywords":"Medicine; Metastatic Urothelial Carcinoma; Urothelial carcinoma; Oncology; Carcinoma; Internal medicine; Cancer; Bladder cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00003480504,0.0001532181,0.0004273213,0.00005276186,0.00001719836,0.000005808518,0.00006140189,0.0000306598,0.0004215517],"category_scores_gemma":[0.00003100383,0.0001096111,0.00005452755,0.0002352676,0.00005249294,0.00005466939,0.00001417818,0.0001033806,0.000006280385],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009677576,"about_ca_system_score_gemma":0.0003947818,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003626169,"about_ca_topic_score_gemma":0.00005472577,"domain_scores_codex":[0.9989352,0.00003099864,0.0002895203,0.000242414,0.0003137742,0.0001880891],"domain_scores_gemma":[0.9994912,0.00002162255,0.000101657,0.0001574089,0.00007812094,0.0001500456],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.7942166,0.004168958,0.1779003,0.0004510184,0.0005068257,0.0001473133,0.003141257,0.00002721006,0.002460284,0.00005437284,0.001071035,0.01585484],"study_design_scores_gemma":[0.8782101,0.02652647,0.08247239,0.0002164292,0.0007037377,0.000001059396,0.0001361445,0.0001101496,0.008930358,0.0000241395,0.00239137,0.0002776041],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969141,0.0002606328,0.00002589664,0.0003595676,0.0001066772,0.001236157,0.0003035884,0.00001619327,0.0007772063],"genre_scores_gemma":[0.9988559,0.00001082179,0.0001703177,0.0005351491,0.0001561959,0.0001445545,0.00002963733,0.00002792391,0.00006951571],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09542793,"threshold_uncertainty_score":0.4615695,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03335126072263959,"score_gpt":0.3069385911879105,"score_spread":0.2735873304652709,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}