{"id":"W3048162181","doi":"10.1002/art.41483","title":"Association of a Serum Protein Signature With Rheumatoid Arthritis Development","year":2020,"lang":"en","type":"article","venue":"Arthritis & Rheumatology","topic":"Rheumatoid Arthritis Research and Therapies","field":"Medicine","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"Institute of Musculoskeletal Health and Arthritis; Canadian Institutes of Health Research","keywords":"Rheumatoid arthritis; Medicine; Cohort; Biomarker; Immunology; Proteome; Disease; Proteomics; Internal medicine; Rheumatoid factor; Oncology; Bioinformatics; Biology; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000345797,0.0003490441,0.001129984,0.0001742089,0.0001933303,0.00004233473,0.0002031178,0.0002992713,0.0008619724],"category_scores_gemma":[0.000527742,0.0003193555,0.0001353141,0.0004855958,0.000238525,0.0002336875,0.0000998491,0.0005837661,0.0002247152],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000843005,"about_ca_system_score_gemma":0.0006258241,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005489296,"about_ca_topic_score_gemma":0.000436065,"domain_scores_codex":[0.9967743,0.0001903391,0.0008747123,0.000562324,0.0008036367,0.0007947587],"domain_scores_gemma":[0.9982875,0.0001368509,0.0003944161,0.0003083257,0.0004409305,0.0004319954],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"not_applicable","study_design_scores_codex":[0.002523774,0.000853634,0.4976737,0.0006937044,0.001964786,0.0009117465,0.009477815,0.00001018937,0.0226225,0.008179252,0.01070115,0.4443877],"study_design_scores_gemma":[0.07824396,0.01197336,0.1039022,0.020757,0.00002788822,0.007970117,0.004328538,0.0004787872,0.3402463,0.001973645,0.4268429,0.003255302],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9680976,0.01958528,0.0003208053,0.009690288,0.00007108718,0.001060796,0.00004255893,0.0002264681,0.0009050748],"genre_scores_gemma":[0.9668027,0.02840625,0.00395491,0.0004029801,0.00001858539,0.0001657983,0.00005139728,0.00006504574,0.0001322879],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4411324,"threshold_uncertainty_score":0.9999259,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008198638150019519,"score_gpt":0.2226074854782821,"score_spread":0.2144088473282625,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}