{"id":"W3048309245","doi":"10.2174/1574893615999200601130946","title":"A Phase I Study of OMN54 (Aneustat™) in Patients with Advanced Malignancies","year":2020,"lang":"en","type":"article","venue":"Clinical Cancer Drugs","topic":"Flavonoids in Medical Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"","keywords":"Medicine; Dosing; Pharmacokinetics; Internal medicine; Toxicity; Adverse effect; Cmax; Gastroenterology; Pharmacology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006215237,0.000718232,0.001143488,0.0002344812,0.0002081598,0.0003615383,0.0004309706,0.0004360785,0.002699946],"category_scores_gemma":[0.0003412794,0.0002434127,0.0005832568,0.0002400713,0.000451084,0.00036698,0.0002197071,0.001087624,0.0006461937],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003909118,"about_ca_system_score_gemma":0.0007777913,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000441902,"about_ca_topic_score_gemma":0.001258356,"domain_scores_codex":[0.9998852,0.00004230801,0.000008905378,0.00002228655,0.0000147133,0.00002663055],"domain_scores_gemma":[0.9997548,0.00003053671,0.00005071914,0.00002293864,0.00002318856,0.0001176351],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.3729801,0.07906467,0.03506573,0.002071186,0.001236558,0.001165466,0.0004635899,0.003286314,0.22513,0.0005452779,0.008706335,0.2702848],"study_design_scores_gemma":[0.211162,0.7365817,0.0291258,0.00006958016,0.0004944253,0.00134419,0.00009775557,0.001111092,0.009183067,0.0001837269,0.01061441,0.00003242475],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957123,0.001394807,0.000313694,0.0002026338,0.00005719148,0.000758174,0.0004174871,0.00005136516,0.001092407],"genre_scores_gemma":[0.9902626,0.001984914,0.001845723,0.0005720554,0.0001102964,0.00112356,0.001940448,0.0000197829,0.002140564],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002699946,"threshold_uncertainty_score":0.00903219,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07591744844348226,"score_gpt":0.4691288127341337,"score_spread":0.3932113642906515,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}