{"id":"W3048343326","doi":"10.1038/s41598-020-69832-z","title":"Comparative structural analyses and nucleotide-binding characterization of the four KH domains of FUBP1","year":2020,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Genetics and Neurodevelopmental Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Novartis Pharma; Ministero dello Sviluppo Economico; Genome Canada; Fundação de Amparo à Pesquisa do Estado de São Paulo; Ontario Ministry of Economic Development and Innovation; Wellcome Trust; European Commission; CALIPSOplus; European Federation of Pharmaceutical Industries and Associations; Merck KGaA; Deutsche Krebshilfe; Pfizer","keywords":"Computational biology; Biology; Bioinformatics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007791218,0.0002874879,0.0002402043,0.0002827775,0.0001839511,0.0001628713,0.0002559854,0.0001957934,0.001282527],"category_scores_gemma":[0.0002401016,0.0001206998,0.0002510383,0.0002696956,0.0001328999,0.0001936041,0.0001585461,0.0002629519,0.0002916991],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003275371,"about_ca_system_score_gemma":0.0001608173,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001876054,"about_ca_topic_score_gemma":0.0017052,"domain_scores_codex":[0.9999515,0.000006075857,0.000003734484,0.00001258276,0.00001469949,0.00001150783],"domain_scores_gemma":[0.9999024,0.00001653774,0.00002783543,0.000007263548,0.00001709602,0.00002892445],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003567161,0.00003789303,0.003401022,0.0001292982,0.00003087051,0.0002142328,0.000110721,0.000853909,0.9902884,0.0002406195,0.0001107284,0.004225628],"study_design_scores_gemma":[0.00005946355,0.0005592048,0.3156666,0.00004695201,0.0002449025,0.002770626,0.0004723885,0.01454538,0.6492058,0.0006375585,0.01572996,0.0000613041],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968252,0.001049079,0.001148771,0.00003494063,0.000005029673,0.000006025284,0.0004230071,0.00001757716,0.0004903651],"genre_scores_gemma":[0.9941689,0.000539055,0.002123988,0.00003001701,0.000006370016,0.00001147873,0.002442565,0.000009344237,0.0006683517],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001876054,"threshold_uncertainty_score":0.004290462,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0372073147879964,"score_gpt":0.2802213792341877,"score_spread":0.2430140644461913,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}