{"id":"W3048402355","doi":"10.1002/ange.201914797","title":"Hydrogen Bond Assisted <scp>l</scp> to <scp>d</scp> Conversion of α‐Amino Acids","year":2020,"lang":"en","type":"article","venue":"Angewandte Chemie","topic":"Chemical Synthesis and Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Enantiopure drug; Chemistry; Diastereomer; Epimer; Hydrogen bond; Amino acid; Yield (engineering); Vicinal; Salt (chemistry); Ternary operation; Diamine; Solubility; Hydrolysis; Organic chemistry; Stereochemistry; Combinatorial chemistry; Catalysis; Molecule; Enantioselective synthesis; Materials science","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001043105,0.0002472567,0.0001536627,0.00008401863,0.0001371923,0.000179406,0.0002684465,0.0001541911,0.001503178],"category_scores_gemma":[0.0001742229,0.0001278692,0.000103172,0.0001063648,0.0001644082,0.0001640502,0.000200803,0.0003869501,0.0004161643],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002932467,"about_ca_system_score_gemma":0.0002158798,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006153745,"about_ca_topic_score_gemma":0.0009930511,"domain_scores_codex":[0.9999361,0.000007158849,0.000005003844,0.0000168335,0.00001570571,0.00001920732],"domain_scores_gemma":[0.99994,0.00000836391,0.00001522043,0.000009753292,0.00001418514,0.00001241459],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006279478,0.00001904071,0.0001141211,0.00005805032,0.000006130935,0.0000962169,0.0000207373,0.000222431,0.9965629,0.0005081422,0.0001929057,0.002136437],"study_design_scores_gemma":[0.000007797675,0.00004921918,0.0002044347,0.00000177879,0.000002357737,0.00004817053,0.000007200344,0.001126118,0.9971387,0.00004993247,0.001361368,0.000002892391],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9831167,0.0003027811,0.009155823,0.00009998162,0.00003744758,0.00004159119,0.0002628213,0.0002275397,0.006755244],"genre_scores_gemma":[0.9962016,0.0001218835,0.002504108,0.00002512693,0.000002157051,0.00001419692,0.0001054193,0.00003749368,0.0009880478],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001503178,"threshold_uncertainty_score":0.005028605,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01554109211837206,"score_gpt":0.2292825087195322,"score_spread":0.2137414166011601,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}