{"id":"W3048402355","doi":"10.1002/ange.201914797","title":"Hydrogen Bond Assisted <scp>l</scp> to <scp>d</scp> Conversion of α‐Amino Acids","year":2020,"lang":"en","type":"article","venue":"Angewandte Chemie","topic":"Chemical Synthesis and Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Enantiopure drug; Chemistry; Diastereomer; Epimer; Hydrogen bond; Amino acid; Yield (engineering); Vicinal; Salt (chemistry); Ternary operation; Diamine; Solubility; Hydrolysis; Organic chemistry; Stereochemistry; Combinatorial chemistry; Catalysis; Molecule; Enantioselective synthesis; Materials science","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001238653,0.0002808261,0.0004230877,0.00004163375,0.00006517265,0.00002574645,0.0003857787,0.0002862571,0.00004106908],"category_scores_gemma":[0.001020717,0.0002650965,0.0003598309,0.0003400872,0.00009183698,0.000007365391,0.0002940492,0.0001221592,0.00006275973],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002375072,"about_ca_system_score_gemma":0.00004993036,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002142187,"about_ca_topic_score_gemma":0.000003616355,"domain_scores_codex":[0.9983541,0.00002412892,0.0003576302,0.0005958793,0.0002774397,0.0003908539],"domain_scores_gemma":[0.9987862,0.0001112669,0.0001625586,0.0004116429,0.0001229901,0.0004053394],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000008933447,0.00007100922,0.002529625,0.00007314337,0.0001766797,0.000005944623,0.0001606763,0.000004267597,0.9410393,0.000003202211,0.0557217,0.0002054783],"study_design_scores_gemma":[0.0003561472,0.0001096365,0.0003889125,0.00001797889,0.0001087384,0.000003239138,0.0002672276,0.00001047803,0.76798,0.000006959902,0.2306919,0.0000587843],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9881013,0.0009755879,0.0001211575,0.0003239228,0.0000341726,0.0001309195,0.00008772378,0.00003000155,0.01019523],"genre_scores_gemma":[0.9953494,0.0001748191,0.0004099322,0.001336574,0.0003257802,0.00001605514,0.0003140131,0.00003980937,0.002033631],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1749702,"threshold_uncertainty_score":0.9999802,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01554109211837206,"score_gpt":0.2292825087195322,"score_spread":0.2137414166011601,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}