{"id":"W3048483421","doi":"10.1152/jn.00339.2020","title":"Early life stress facilitates synapse premature unsilencing to enhance AMPA receptor function in the developing hippocampus","year":2020,"lang":"en","type":"article","venue":"Journal of Neurophysiology","topic":"Stress Responses and Cortisol","field":"Neuroscience","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Carleton University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Neuroscience; AMPA receptor; Synapse; Hippocampal formation; Silent synapse; Hippocampus; Psychology; Biology; Glutamate receptor; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001120752,0.000323632,0.0002890498,0.0001641329,0.000125741,0.0002139844,0.0002998312,0.0002437073,0.001297534],"category_scores_gemma":[0.0002263668,0.000154549,0.0003082364,0.00005781219,0.0003168182,0.0002188149,0.0003693044,0.0008491457,0.0001885591],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002475062,"about_ca_system_score_gemma":0.0002415205,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001047881,"about_ca_topic_score_gemma":0.003004824,"domain_scores_codex":[0.9998674,0.0000154744,0.00001283786,0.00003359545,0.00002853363,0.000042135],"domain_scores_gemma":[0.9997582,0.00002005126,0.00007755102,0.00003255107,0.00002402183,0.00008759393],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002854269,0.00005701041,0.0009253888,0.00004356732,0.000009552525,0.0002745222,0.00005951971,0.00003929213,0.9959183,0.000100521,0.00005226892,0.002234723],"study_design_scores_gemma":[0.00004984423,0.002046568,0.127896,0.00004419704,0.00005118436,0.001094957,0.0007409115,0.001260488,0.8643497,0.0005591515,0.001874534,0.00003244323],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977202,0.0005967038,0.00107802,0.00007738068,0.0000373607,0.000006987412,0.0001068186,0.00003085753,0.0003456183],"genre_scores_gemma":[0.9976512,0.0003996934,0.0005963348,0.00006310964,0.000006472782,0.00001664103,0.00009080138,0.00001284573,0.001163058],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001297534,"threshold_uncertainty_score":0.004340708,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02975274276479489,"score_gpt":0.2749304918541169,"score_spread":0.245177749089322,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}