{"id":"W3048497751","doi":"10.1080/00365521.2020.1803396","title":"Faecal microbiota signatures of IBD and their relation to diagnosis, disease phenotype, inflammation, treatment escalation and anti-TNF response in a European Multicentre Study (IBD-Character)","year":2020,"lang":"en","type":"article","venue":"Scandinavian Journal of Gastroenterology","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":43,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Crohn's and Colitis UK","keywords":"Dysbiosis; Eubacterium; Inflammatory bowel disease; Firmicutes; Ulcerative colitis; Gastroenterology; Medicine; Internal medicine; Gut flora; Crohn's disease; Ruminococcus; Faecal calprotectin; Faecalibacterium prausnitzii; Immunology; Biology; Disease; Calprotectin","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002886439,0.0001450583,0.0002623599,0.0001167969,0.00004028774,0.00001497401,0.00007892284,0.00004968394,0.000004576471],"category_scores_gemma":[0.0001002193,0.0001178148,0.00004658766,0.00006069506,0.00005040578,0.00001250118,0.00005955122,0.0001071,7.760854e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002698217,"about_ca_system_score_gemma":0.00003232894,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005619418,"about_ca_topic_score_gemma":0.0000449509,"domain_scores_codex":[0.9985818,0.000556209,0.0004299058,0.0002125147,0.00004860188,0.00017102],"domain_scores_gemma":[0.9993138,0.00002481993,0.0002699614,0.000096606,0.00007853378,0.0002163201],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.008635833,0.0001566555,0.6249233,0.0000172336,0.00004294103,0.00002155875,0.00189851,0.0000890498,0.36358,7.787434e-7,0.00003814239,0.0005960178],"study_design_scores_gemma":[0.002968909,0.006051074,0.9880876,0.00006099895,0.00003805269,0.00002254821,0.0003933884,0.00002909033,0.002123331,0.000001937402,0.0001625053,0.0000605638],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969293,0.0003032925,0.0002117044,0.002112933,0.00005232507,0.0003501962,0.00003687209,0.000002140607,0.000001270744],"genre_scores_gemma":[0.9992929,0.0001747135,0.0001405684,0.0002456572,0.0001026212,0.000002922799,0.00002437442,0.00001318314,0.000003055546],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3631643,"threshold_uncertainty_score":0.4804348,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009303983370743325,"score_gpt":0.2387854052372678,"score_spread":0.2294814218665245,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}