{"id":"W3048497751","doi":"10.1080/00365521.2020.1803396","title":"Faecal microbiota signatures of IBD and their relation to diagnosis, disease phenotype, inflammation, treatment escalation and anti-TNF response in a European Multicentre Study (IBD-Character)","year":2020,"lang":"en","type":"article","venue":"Scandinavian Journal of Gastroenterology","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":43,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Crohn's and Colitis UK","keywords":"Dysbiosis; Eubacterium; Inflammatory bowel disease; Firmicutes; Ulcerative colitis; Gastroenterology; Medicine; Internal medicine; Gut flora; Crohn's disease; Ruminococcus; Faecal calprotectin; Faecalibacterium prausnitzii; Immunology; Biology; Disease; Calprotectin","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001518129,0.0005669025,0.0005345698,0.001101242,0.0006364684,0.0007216061,0.0003935296,0.0007584236,0.0009121404],"category_scores_gemma":[0.002624572,0.00036862,0.0004608839,0.001156211,0.0004001367,0.0003782898,0.0006255679,0.0003263639,0.0002081362],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003209591,"about_ca_system_score_gemma":0.000200583,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001887442,"about_ca_topic_score_gemma":0.001833552,"domain_scores_codex":[0.9987644,0.0005282953,0.0001270652,0.0003361678,0.0001350514,0.0001091161],"domain_scores_gemma":[0.9981365,0.0002366121,0.000856088,0.0002518285,0.0001906951,0.0003281899],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0008873248,0.00009627361,0.9961627,0.00001722726,0.00008531997,0.0001503763,0.0001107193,0.0000317822,0.001250123,0.00001022799,0.00004922406,0.001148673],"study_design_scores_gemma":[0.000024858,0.0002940832,0.9989889,0.000003199597,0.00002953498,0.0003870571,0.00005150967,0.0000525462,0.00007538397,0.000005971594,0.00008404902,0.000002729072],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9993761,0.000214432,0.0001203185,0.00001140155,0.000002484702,0.00001583657,0.0001499862,0.000002597814,0.0001068654],"genre_scores_gemma":[0.9989905,0.0000726485,0.0004239957,0.00002537379,0.000008754489,0.00002101862,0.0003334725,0.000002485113,0.0001217469],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001887442,"threshold_uncertainty_score":0.008028746,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009303983370743325,"score_gpt":0.2387854052372678,"score_spread":0.2294814218665245,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}