{"id":"W3048611368","doi":"10.1126/scitranslmed.aaz8926","title":"Donor fecal microbiota transplantation ameliorates intestinal graft-versus-host disease in allogeneic hematopoietic cell transplant recipients","year":2020,"lang":"en","type":"article","venue":"Science Translational Medicine","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":157,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"Nederlandse Organisatie voor Wetenschappelijk Onderzoek; Landsteiner Foundation for Blood Transfusion Research","keywords":"Fecal bacteriotherapy; Graft-versus-host disease; Transplantation; Hematopoietic stem cell transplantation; Feces; Immunology; Hematopoietic cell; Gut flora; Disease; Host (biology); Biology; Medicine; Haematopoiesis; Microbiology; Stem cell; Antibiotics; Internal medicine; Clostridium difficile; Ecology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000152271,0.0003162578,0.000192423,0.0001901814,0.0001234681,0.0001540303,0.0001143876,0.0001233307,0.0009202032],"category_scores_gemma":[0.000165135,0.00005534746,0.00009705764,0.00008100725,0.0001434415,0.0001337123,0.0001334825,0.0003300057,0.0001677231],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008422375,"about_ca_system_score_gemma":0.0001420896,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001678245,"about_ca_topic_score_gemma":0.0003984447,"domain_scores_codex":[0.9999501,0.00001632904,0.000003490361,0.000004667969,0.000009188652,0.00001633178],"domain_scores_gemma":[0.9999378,0.000006142189,0.00001166807,0.000006474299,0.000003859412,0.00003414136],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.008476953,0.003573417,0.007682377,0.000281143,0.00008953502,0.00110371,0.0001149805,0.0005031103,0.7791122,0.0001879341,0.0008933871,0.1979813],"study_design_scores_gemma":[0.002991737,0.1295402,0.2322252,0.0001734022,0.0005221781,0.01148147,0.000530596,0.005503302,0.6021884,0.001192729,0.01360868,0.00004201299],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970252,0.001123172,0.0004561932,0.00009436061,0.00004243515,0.00001765623,0.00003087897,0.00007298113,0.001137238],"genre_scores_gemma":[0.998328,0.0006561592,0.00041129,0.00006875693,0.00002450262,0.000006826731,0.00006853422,0.000006890058,0.0004289825],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009202032,"threshold_uncertainty_score":0.003078401,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03619057174825802,"score_gpt":0.2931123135513876,"score_spread":0.2569217418031296,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}