{"id":"W3048637915","doi":"10.1093/glycob/cwaa075","title":"O-linked mucin-type glycosylation regulates the transcriptional programme downstream of EGFR","year":2020,"lang":"en","type":"article","venue":"Glycobiology","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Medical Research Council; Novo Nordisk Fonden; Medical Research Council Canada; Cancer Research UK","keywords":"Glycosylation; Mucin; Downstream (manufacturing); Chemistry; Cell biology; N-linked glycosylation; Glycoprotein; Biology; Biochemistry; Glycan; Business","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002354879,0.000165143,0.0001945985,0.00004002174,0.000101737,0.00001567815,0.000323079,0.0002378734,0.0002529379],"category_scores_gemma":[0.0003041755,0.0001187325,0.0001280729,0.000269431,0.0002921673,0.000005464512,0.00008416438,0.000168656,0.00005851854],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001157876,"about_ca_system_score_gemma":0.0001317022,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004266597,"about_ca_topic_score_gemma":0.00003866578,"domain_scores_codex":[0.9986202,0.0001704689,0.0003303019,0.0003750471,0.0001661955,0.0003378032],"domain_scores_gemma":[0.9991634,0.00003424569,0.0001130794,0.000314374,0.0002560745,0.000118788],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0008166488,0.00006621514,0.002913392,0.00002995385,0.00007859266,0.000001971234,0.0001382651,0.0001355977,0.9836637,0.002004722,0.001312818,0.008838113],"study_design_scores_gemma":[0.002522769,0.003027328,0.02597701,0.000015751,0.0000442039,0.00005519023,0.0002060477,0.001293073,0.4442197,0.0007022162,0.5215293,0.0004073825],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9923855,0.0008607433,0.0007452075,0.003978181,0.0001901171,0.0005717482,0.00004033023,0.00003129725,0.001196843],"genre_scores_gemma":[0.9975628,0.0001285708,0.000491059,0.0005778352,0.000337128,0.00002877128,0.0005571339,0.00001767792,0.000299005],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.539444,"threshold_uncertainty_score":0.484177,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03491719553495777,"score_gpt":0.2659070474988534,"score_spread":0.2309898519638956,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}