{"id":"W3048899545","doi":"10.1186/s12885-020-07217-1","title":"Breast cancer diagnosis is associated with relative left ventricular hypertrophy and elevated endothelin-1 signaling","year":2020,"lang":"en","type":"article","venue":"BMC Cancer","topic":"Chemotherapy-induced cardiotoxicity and mitigation","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Cancer Foundation; University of Alberta","funders":"University of Alberta; Canadian Institutes of Health Research; Alberta Innovates; Women and Children's Health Research Institute; Children's Health Research Institute","keywords":"Breast cancer; Medicine; Cancer; Internal medicine; Oncology; Surgical oncology; Endothelin 1; Left ventricular hypertrophy; CA15-3; Cardiology; Receptor; Blood pressure","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006202102,0.0001727361,0.0003376584,0.00003925872,0.00008312971,0.00002078387,0.00003856037,0.0001140367,0.0006838249],"category_scores_gemma":[0.00004653532,0.0001405538,0.00008993117,0.0002514529,0.00005792467,0.0001030529,0.00001406304,0.0002099805,0.000005142253],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002206876,"about_ca_system_score_gemma":0.0002016847,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003085837,"about_ca_topic_score_gemma":0.00006533992,"domain_scores_codex":[0.9989856,0.00004616992,0.0001656265,0.0003223857,0.0002708391,0.0002094188],"domain_scores_gemma":[0.9993732,0.00008528664,0.0001109808,0.00009761311,0.000162372,0.0001705447],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00118126,0.0001503841,0.4797038,0.0002162039,0.001671283,0.0001368934,0.004178128,0.0003600044,0.5057474,0.0000276798,0.001789393,0.004837652],"study_design_scores_gemma":[0.006096866,0.0002524848,0.06148607,0.0008934615,0.0007903885,0.00009804469,0.0002328455,0.001173863,0.9263448,0.0000328914,0.002201643,0.0003966322],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9924315,0.00197397,0.0003248816,0.004313717,0.00004630294,0.0004330006,0.0003139069,0.00007867396,0.00008408217],"genre_scores_gemma":[0.994391,0.000761224,0.0001131739,0.003993865,0.000328568,0.0001481463,0.00002441402,0.00003919509,0.0002004274],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4205974,"threshold_uncertainty_score":0.7487404,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02278961078952357,"score_gpt":0.2531804699886492,"score_spread":0.2303908591991257,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}