{"id":"W3048922161","doi":"10.7490/f1000research.1118235.1","title":"Expansion of reactome functional interaction network to allow exposure of knowledge space of understudied proteins in the context of biological pathways","year":2020,"lang":"en","type":"article","venue":"Faculty of 1000 Research Ltd","topic":"Bioinformatics and Genomic Networks","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Ontario Institute for Cancer Research; Research Canada","funders":"","keywords":"Open peer review; Plant biology; Context (archaeology); Neuroscience; Computational biology; Space (punctuation); Biology; Computer science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001059196,0.00009514875,0.000286747,0.0000543602,0.00002785908,0.000002799737,0.000261691,0.000148516,0.00001695071],"category_scores_gemma":[0.0002622481,0.00006522288,0.0001066863,0.0003012237,0.0002145315,0.000004810538,0.0002178203,0.0001958874,0.000002052225],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001474327,"about_ca_system_score_gemma":0.0001261208,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007518088,"about_ca_topic_score_gemma":0.00008744667,"domain_scores_codex":[0.9986587,0.0002163386,0.0004777432,0.000162884,0.0002919711,0.0001924219],"domain_scores_gemma":[0.9988882,0.0001102003,0.0002100677,0.0002180367,0.0005196755,0.00005379557],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001336283,0.0002320655,0.002520357,0.0002446203,0.00008557037,5.378059e-7,0.003499856,0.0005776495,0.9774641,0.0006673118,0.01020242,0.00316925],"study_design_scores_gemma":[0.002405028,0.009294405,0.03934161,0.0005162701,0.00002095501,0.000003645672,0.02047422,0.0008597656,0.906401,0.0003948878,0.02001806,0.0002701055],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9962234,0.0003736973,0.0009546701,0.0009030925,0.00003428087,0.0005199359,0.0001048965,0.000001705808,0.0008843601],"genre_scores_gemma":[0.9991648,0.0001113446,0.0004202865,0.00003698554,0.00007297193,0.00001653087,0.0001326787,0.000005656531,0.00003870739],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07106303,"threshold_uncertainty_score":0.2659712,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09836531728034015,"score_gpt":0.3343260183650807,"score_spread":0.2359607010847406,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}