{"id":"W3048939827","doi":"10.1002/jcp.29997","title":"Molecular characteristics and physiological roles of Na<sup>+</sup>–K<sup>+</sup>–Cl<sup>−</sup> cotransporter 2","year":2020,"lang":"en","type":"review","venue":"Journal of Cellular Physiology","topic":"Ion Transport and Channel Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Université Laval","funders":"Canadian Institutes of Health Research; Kidney Foundation of Canada","keywords":"Cotransporter; Chemistry; Ion transporter; Ion; Symporter; Loop of Henle; Biophysics; Membrane; Biochemistry; Sodium; Nephron; Biology; Transporter; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002965647,0.0006013896,0.000688242,0.001764865,0.0001714755,0.0007376229,0.0006010769,0.0006752576,0.002035263],"category_scores_gemma":[0.0004365158,0.0001850665,0.0002083141,0.001764991,0.000389243,0.0009429088,0.0004193542,0.001137006,0.00180954],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005033934,"about_ca_system_score_gemma":0.0005665495,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006399473,"about_ca_topic_score_gemma":0.0007653357,"domain_scores_codex":[0.9999202,0.00001242854,0.00001381916,0.00001819452,0.00002652118,0.000008815596],"domain_scores_gemma":[0.9998653,0.00005350157,0.00001789962,0.000004664485,0.00004399845,0.00001468245],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001646938,0.00007373673,0.0003429108,0.01528955,0.00006519593,0.0003607172,0.00008359451,0.0005842539,0.006399596,0.008632602,0.04144914,0.926554],"study_design_scores_gemma":[0.00001108329,0.00008074152,0.001189242,0.001646308,0.00006443478,0.001636729,0.00005433684,0.0001279262,0.001036702,0.00200642,0.9921259,0.00002025505],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002348666,0.997698,0.000136994,0.0003218336,0.0003250359,0.000002636806,0.00002238564,0.000005541579,0.001252682],"genre_scores_gemma":[0.001101559,0.9974616,0.0001325857,0.0001742268,0.0002070568,0.000005157554,0.00003598818,0.000001168777,0.0008807629],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002035263,"threshold_uncertainty_score":0.006808639,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01793767944889671,"score_gpt":0.2494779157884322,"score_spread":0.2315402363395355,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}